Tags

Type your tag names separated by a space and hit enter

Effectiveness of H1N1/09 monovalent and trivalent influenza vaccines against hospitalization with laboratory-confirmed H1N1/09 influenza in Australia: a test-negative case control study.
Vaccine 2011; 29(43):7320-5V

Abstract

We aimed to estimate the effectiveness of H1N1/09 containing influenza vaccines against hospitalization from influenza in Australia. We performed a test-negative case control study in patients hospitalized in 15 sentinel Australian hospitals between March and November 2010, comparing influenza vaccination (H1N1/09 monovalent or 2010 seasonal trivalent) in hospitalized patients with PCR-confirmed influenza compared to PCR-negative controls. Between March and November 2010, 1169 hospitalized patients were tested for suspected influenza, of which influenza vaccine status was ascertained in 165/238 patients with H1N1/09 influenza, 40/64 with seasonal influenza and 558/867 test negative controls; 24% of H1N1/09 cases, 43% of seasonal influenza cases and 54% of controls were vaccinated. VE against hospitalisation with H1N1/09 influenza after adjusting for age, medical comorbidities and pregnancy status was estimated at 49% (95% CI: 13%, 70%). Influenza vaccination was associated with a reduction in hospitalisation caused by H1N1/09 influenza in the 2010 southern hemisphere winter season.

Authors+Show Affiliations

Monash University, Australia. allen.cheng@monash.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21810450

Citation

Cheng, Allen C., et al. "Effectiveness of H1N1/09 Monovalent and Trivalent Influenza Vaccines Against Hospitalization With Laboratory-confirmed H1N1/09 Influenza in Australia: a Test-negative Case Control Study." Vaccine, vol. 29, no. 43, 2011, pp. 7320-5.
Cheng AC, Kotsimbos T, Kelly HA, et al. Effectiveness of H1N1/09 monovalent and trivalent influenza vaccines against hospitalization with laboratory-confirmed H1N1/09 influenza in Australia: a test-negative case control study. Vaccine. 2011;29(43):7320-5.
Cheng, A. C., Kotsimbos, T., Kelly, H. A., Irving, L. B., Bowler, S. D., Brown, S. G., ... Kelly, P. M. (2011). Effectiveness of H1N1/09 monovalent and trivalent influenza vaccines against hospitalization with laboratory-confirmed H1N1/09 influenza in Australia: a test-negative case control study. Vaccine, 29(43), pp. 7320-5. doi:10.1016/j.vaccine.2011.07.087.
Cheng AC, et al. Effectiveness of H1N1/09 Monovalent and Trivalent Influenza Vaccines Against Hospitalization With Laboratory-confirmed H1N1/09 Influenza in Australia: a Test-negative Case Control Study. Vaccine. 2011 Oct 6;29(43):7320-5. PubMed PMID: 21810450.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effectiveness of H1N1/09 monovalent and trivalent influenza vaccines against hospitalization with laboratory-confirmed H1N1/09 influenza in Australia: a test-negative case control study. AU - Cheng,Allen C, AU - Kotsimbos,Tom, AU - Kelly,Heath A, AU - Irving,Louis B, AU - Bowler,Simon D, AU - Brown,Simon G A, AU - Holmes,Mark, AU - Jenkins,Christine R, AU - Thompson,Philip, AU - Simpson,Graham, AU - Wood-Baker,Richard, AU - Senanayake,Sanjaya N, AU - Brady,Stephen J, AU - Paterson,David L, AU - Wark,Peter A, AU - Upham,John W, AU - Korman,Tony M, AU - Dwyer,Dominic E, AU - Waterer,Grant W, AU - Kelly,Paul M, Y1 - 2011/07/31/ PY - 2011/03/28/received PY - 2011/07/04/revised PY - 2011/07/19/accepted PY - 2011/8/4/entrez PY - 2011/8/4/pubmed PY - 2012/3/30/medline SP - 7320 EP - 5 JF - Vaccine JO - Vaccine VL - 29 IS - 43 N2 - We aimed to estimate the effectiveness of H1N1/09 containing influenza vaccines against hospitalization from influenza in Australia. We performed a test-negative case control study in patients hospitalized in 15 sentinel Australian hospitals between March and November 2010, comparing influenza vaccination (H1N1/09 monovalent or 2010 seasonal trivalent) in hospitalized patients with PCR-confirmed influenza compared to PCR-negative controls. Between March and November 2010, 1169 hospitalized patients were tested for suspected influenza, of which influenza vaccine status was ascertained in 165/238 patients with H1N1/09 influenza, 40/64 with seasonal influenza and 558/867 test negative controls; 24% of H1N1/09 cases, 43% of seasonal influenza cases and 54% of controls were vaccinated. VE against hospitalisation with H1N1/09 influenza after adjusting for age, medical comorbidities and pregnancy status was estimated at 49% (95% CI: 13%, 70%). Influenza vaccination was associated with a reduction in hospitalisation caused by H1N1/09 influenza in the 2010 southern hemisphere winter season. SN - 1873-2518 UR - https://www.unboundmedicine.com/medline/citation/21810450/Effectiveness_of_H1N1/09_monovalent_and_trivalent_influenza_vaccines_against_hospitalization_with_laboratory_confirmed_H1N1/09_influenza_in_Australia:_a_test_negative_case_control_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(11)01137-6 DB - PRIME DP - Unbound Medicine ER -