Tags

Type your tag names separated by a space and hit enter

Prevalence of vitamin D deficiency and secondary hyperparathyroidism during winter in pre-menopausal Bangladeshi and Somali immigrant and ethnic Finnish women: associations with forearm bone mineral density.
Br J Nutr. 2012 Jan; 107(2):277-83.BJ

Abstract

Secondary hyperparathyroidism (SHPT) is one of the outcomes of vitamin D deficiency that negatively affects bone metabolism. We studied the ethnic differences in vitamin D status in Finland and its effect on serum intact parathyroid hormone (S-iPTH) concentration and bone traits. The study was done in the Helsinki area (60°N) during January-February 2008. A total of 143 healthy women (20-48 years of age) from two groups of immigrant women (Bangladeshi, n 34 and Somali, n 48), and a group of ethnic Finnish women (n 61) were studied in a cross-sectional setting. Serum concentrations of 25-hydroxyvitamin D (S-25OHD) and S-iPTH were measured. Peripheral quantitative computed tomography measurements were taken at 4 and 66 % of the forearm length. In all groups, the distribution of S-25OHD was shifted towards the lower limit of the normal range. A high prevalence of vitamin D insufficiency (S-25OHD < 50 nmol/l) was observed (89·6 %) in the Somali group. The prevalence of SHPT (S-iPTH>65 ng/l) was higher (79·1 %) in Somali women than in Finnish women (16 %). There was a significant association between S-25OHD and S-iPTH (r - 0·49, P < 0·001). Ethnicity and S-25OHD together explained 30 % of the variation in S-iPTH. The total bone mass at all sites of the forearm, fracture load and stress-strain index was higher (P < 0·001) in Bangladeshi and Finnish women than in Somali women. The high prevalence of hypovitaminosis D, SHPT and low bone status in Somali women indicates a higher risk of osteoporosis.

Authors+Show Affiliations

Calcium Research Unit, Department of Food and Environmental Sciences (Nutrition), University of Helsinki, PO Box 66, 00014 Helsinki, Finland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21824446

Citation

Islam, Md Zahirul, et al. "Prevalence of Vitamin D Deficiency and Secondary Hyperparathyroidism During Winter in Pre-menopausal Bangladeshi and Somali Immigrant and Ethnic Finnish Women: Associations With Forearm Bone Mineral Density." The British Journal of Nutrition, vol. 107, no. 2, 2012, pp. 277-83.
Islam MZ, Viljakainen HT, Kärkkäinen MU, et al. Prevalence of vitamin D deficiency and secondary hyperparathyroidism during winter in pre-menopausal Bangladeshi and Somali immigrant and ethnic Finnish women: associations with forearm bone mineral density. Br J Nutr. 2012;107(2):277-83.
Islam, M. Z., Viljakainen, H. T., Kärkkäinen, M. U., Saarnio, E., Laitinen, K., & Lamberg-Allardt, C. (2012). Prevalence of vitamin D deficiency and secondary hyperparathyroidism during winter in pre-menopausal Bangladeshi and Somali immigrant and ethnic Finnish women: associations with forearm bone mineral density. The British Journal of Nutrition, 107(2), 277-83. https://doi.org/10.1017/S0007114511002893
Islam MZ, et al. Prevalence of Vitamin D Deficiency and Secondary Hyperparathyroidism During Winter in Pre-menopausal Bangladeshi and Somali Immigrant and Ethnic Finnish Women: Associations With Forearm Bone Mineral Density. Br J Nutr. 2012;107(2):277-83. PubMed PMID: 21824446.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of vitamin D deficiency and secondary hyperparathyroidism during winter in pre-menopausal Bangladeshi and Somali immigrant and ethnic Finnish women: associations with forearm bone mineral density. AU - Islam,Md Zahirul, AU - Viljakainen,Heli T, AU - Kärkkäinen,Merja U M, AU - Saarnio,Elisa, AU - Laitinen,Kalevi, AU - Lamberg-Allardt,Christel, Y1 - 2011/08/09/ PY - 2011/8/10/entrez PY - 2011/8/10/pubmed PY - 2012/3/3/medline SP - 277 EP - 83 JF - The British journal of nutrition JO - Br J Nutr VL - 107 IS - 2 N2 - Secondary hyperparathyroidism (SHPT) is one of the outcomes of vitamin D deficiency that negatively affects bone metabolism. We studied the ethnic differences in vitamin D status in Finland and its effect on serum intact parathyroid hormone (S-iPTH) concentration and bone traits. The study was done in the Helsinki area (60°N) during January-February 2008. A total of 143 healthy women (20-48 years of age) from two groups of immigrant women (Bangladeshi, n 34 and Somali, n 48), and a group of ethnic Finnish women (n 61) were studied in a cross-sectional setting. Serum concentrations of 25-hydroxyvitamin D (S-25OHD) and S-iPTH were measured. Peripheral quantitative computed tomography measurements were taken at 4 and 66 % of the forearm length. In all groups, the distribution of S-25OHD was shifted towards the lower limit of the normal range. A high prevalence of vitamin D insufficiency (S-25OHD < 50 nmol/l) was observed (89·6 %) in the Somali group. The prevalence of SHPT (S-iPTH>65 ng/l) was higher (79·1 %) in Somali women than in Finnish women (16 %). There was a significant association between S-25OHD and S-iPTH (r - 0·49, P < 0·001). Ethnicity and S-25OHD together explained 30 % of the variation in S-iPTH. The total bone mass at all sites of the forearm, fracture load and stress-strain index was higher (P < 0·001) in Bangladeshi and Finnish women than in Somali women. The high prevalence of hypovitaminosis D, SHPT and low bone status in Somali women indicates a higher risk of osteoporosis. SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/21824446/Prevalence_of_vitamin_D_deficiency_and_secondary_hyperparathyroidism_during_winter_in_pre_menopausal_Bangladeshi_and_Somali_immigrant_and_ethnic_Finnish_women:_associations_with_forearm_bone_mineral_density_ L2 - https://www.cambridge.org/core/product/identifier/S0007114511002893/type/journal_article DB - PRIME DP - Unbound Medicine ER -