[Dengue: an emerging infection in travelers].Rev Prat. 2011 Jun; 61(6):755-9.RP
Dengue is a common, mosquito borne, travel-related, viral infection in the tropical traveler caused by an arbovirus. This virus has 4 different serotypes and is responsible for approximately 50 to 100 million cases per year. Its incidence and geographic distribution are clearly increasing lately. Although occurring in tropical endemic areas, sporadic and autochthonous cases have been recently reported in temperate countries including France. The tropical influenza-like clinical presentation is not very specific except for rash. Diagnosis is facilitated by the existence of thrombocytopenia and the early detection of NS1 antigen using rapid test. Hemorragic forms with or without shock syndrome are rare in travelers and represent the severe manifestations especially in children. Their pathophysiology remains controversial. Management is essentially symptomatic. Aspirine should be avoided because of bleeding risk. Beyond individual (travel) or collective (endemic zone) vector control measures, the development of a quadrivalent vaccine seems about to succeed.