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Helichrysum monizii Lowe: phenolic composition and antioxidant potential.
Phytochem Anal. 2012 Jan-Feb; 23(1):72-83.PA

Abstract

INTRODUCTION

In Madeira Archipelago there are four endemic Helichyrsum species and three of them are used in the traditional medicine. Helichrysum monizii is a rare endemism with very scarce information available concerning its uses in the local traditional medicine.

OBJECTIVE

The aim of this work was to study for the first time Helichrysum monizii in terms of its antioxidant capacity and the identification of the phenolic compounds to which that activity is due.

METHODOLOGY

Three different methods of extraction were performed and total phenolic and flavonoid contents of extracts were correlated to radical scavenging and antioxidant capacity by DPPH, ABTS, FRAP and β-carotene assays. An HPLC-DAD-ESI/MS(n) method was employed for the separation and identification of the phenolic and flavonoid components.

RESULTS

The results revealed a high antioxidant potential mainly related to the phenolic profile of the plant. Polar components of methanol extracts of Helichrsyum monizii were detected by a high-performance liquid chromatography/electrospray ionisation tandem mass spectrometry (HPLC-DAD-ESI/MS(n)) method. Thirty-three compounds were identified and 19 of them were identified as quinic acid derivatives.

CONCLUSIONS

The high antioxidant potential Helichrysum monizii was for the first time established. Dicaffeoylquinic acids are the main responsible for that activity.

Authors+Show Affiliations

Centro de Química da Madeira, CCCEE, Universidade da Madeiram, Campus da Penteada, 9000-390, Funchal, Portugal.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21837645

Citation

Gouveia, Sandra, and Paula C. Castilho. "Helichrysum Monizii Lowe: Phenolic Composition and Antioxidant Potential." Phytochemical Analysis : PCA, vol. 23, no. 1, 2012, pp. 72-83.
Gouveia S, Castilho PC. Helichrysum monizii Lowe: phenolic composition and antioxidant potential. Phytochem Anal. 2012;23(1):72-83.
Gouveia, S., & Castilho, P. C. (2012). Helichrysum monizii Lowe: phenolic composition and antioxidant potential. Phytochemical Analysis : PCA, 23(1), 72-83. https://doi.org/10.1002/pca.1326
Gouveia S, Castilho PC. Helichrysum Monizii Lowe: Phenolic Composition and Antioxidant Potential. Phytochem Anal. 2012 Jan-Feb;23(1):72-83. PubMed PMID: 21837645.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Helichrysum monizii Lowe: phenolic composition and antioxidant potential. AU - Gouveia,Sandra, AU - Castilho,Paula C, Y1 - 2011/08/12/ PY - 2010/11/10/received PY - 2011/02/13/revised PY - 2011/02/15/accepted PY - 2011/8/13/entrez PY - 2011/8/13/pubmed PY - 2012/3/30/medline SP - 72 EP - 83 JF - Phytochemical analysis : PCA JO - Phytochem Anal VL - 23 IS - 1 N2 - INTRODUCTION: In Madeira Archipelago there are four endemic Helichyrsum species and three of them are used in the traditional medicine. Helichrysum monizii is a rare endemism with very scarce information available concerning its uses in the local traditional medicine. OBJECTIVE: The aim of this work was to study for the first time Helichrysum monizii in terms of its antioxidant capacity and the identification of the phenolic compounds to which that activity is due. METHODOLOGY: Three different methods of extraction were performed and total phenolic and flavonoid contents of extracts were correlated to radical scavenging and antioxidant capacity by DPPH, ABTS, FRAP and β-carotene assays. An HPLC-DAD-ESI/MS(n) method was employed for the separation and identification of the phenolic and flavonoid components. RESULTS: The results revealed a high antioxidant potential mainly related to the phenolic profile of the plant. Polar components of methanol extracts of Helichrsyum monizii were detected by a high-performance liquid chromatography/electrospray ionisation tandem mass spectrometry (HPLC-DAD-ESI/MS(n)) method. Thirty-three compounds were identified and 19 of them were identified as quinic acid derivatives. CONCLUSIONS: The high antioxidant potential Helichrysum monizii was for the first time established. Dicaffeoylquinic acids are the main responsible for that activity. SN - 1099-1565 UR - https://www.unboundmedicine.com/medline/citation/21837645/Helichrysum_monizii_Lowe:_phenolic_composition_and_antioxidant_potential_ DB - PRIME DP - Unbound Medicine ER -