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Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion.
Clin Ophthalmol. 2011; 5:1031-6.CO

Abstract

PURPOSE

To report the efficacy of grid photocoagulation combined with intravitreal bevacizumab (IVB) for macular edema recurring after previous IVBs associated with retinal vein occlusion (RVO).

METHODS

This retrospective study consisted of 19 eyes with branch retinal vein occlusion (BRVO) and nine eyes with central retinal vein occlusion (CRVO), which were treated with grid photocoagulation combined with IVB for recurrent macular edema after previous IVBs. The mean duration of total follow-up was 29.3 ± 5.8 months.

RESULTS

After this combination therapy, foveal thickness was reduced, significant with slight improvement in visual acuity (VA). At 1 month after treatment, although 25 of the 28 eyes showed complete resolution of the cystoid space, the macular edema recurred to some extent in 19 eyes. Compared with initial values, final foveal thickness was reduced significantly in both BRVO and CRVO groups (P < 0.001), but improvement in VA was significant only for eyes with BRVO (P = 0.012). The total number of IVB was 2.8 ± 0.7 for eyes with either BRVO or CRVO.

CONCLUSION

Grid photocoagulation combined with IVB has a substantial effect on reducing recurrent macular edema associated with RVO, but the effect on visual acuity is limited.

Authors+Show Affiliations

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21845030

Citation

Ogino, Ken, et al. "Grid Photocoagulation Combined With Intravitreal Bevacizumab for Recurrent Macular Edema Associated With Retinal Vein Occlusion." Clinical Ophthalmology (Auckland, N.Z.), vol. 5, 2011, pp. 1031-6.
Ogino K, Tsujikawa A, Murakami T, et al. Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion. Clin Ophthalmol. 2011;5:1031-6.
Ogino, K., Tsujikawa, A., Murakami, T., Muraoka, Y., Kurashige, Y., & Yoshimura, N. (2011). Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion. Clinical Ophthalmology (Auckland, N.Z.), 5, 1031-6. https://doi.org/10.2147/OPTH.S22923
Ogino K, et al. Grid Photocoagulation Combined With Intravitreal Bevacizumab for Recurrent Macular Edema Associated With Retinal Vein Occlusion. Clin Ophthalmol. 2011;5:1031-6. PubMed PMID: 21845030.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion. AU - Ogino,Ken, AU - Tsujikawa,Akitaka, AU - Murakami,Tomoaki, AU - Muraoka,Yuki, AU - Kurashige,Yumiko, AU - Yoshimura,Nagahisa, Y1 - 2011/07/26/ PY - 2011/07/25/received PY - 2011/8/17/entrez PY - 2011/8/17/pubmed PY - 2011/8/17/medline KW - bevacizumab KW - grid laser photocoagulation KW - macular edema KW - optical coherence tomography KW - retinal vein occlusion SP - 1031 EP - 6 JF - Clinical ophthalmology (Auckland, N.Z.) JO - Clin Ophthalmol VL - 5 N2 - PURPOSE: To report the efficacy of grid photocoagulation combined with intravitreal bevacizumab (IVB) for macular edema recurring after previous IVBs associated with retinal vein occlusion (RVO). METHODS: This retrospective study consisted of 19 eyes with branch retinal vein occlusion (BRVO) and nine eyes with central retinal vein occlusion (CRVO), which were treated with grid photocoagulation combined with IVB for recurrent macular edema after previous IVBs. The mean duration of total follow-up was 29.3 ± 5.8 months. RESULTS: After this combination therapy, foveal thickness was reduced, significant with slight improvement in visual acuity (VA). At 1 month after treatment, although 25 of the 28 eyes showed complete resolution of the cystoid space, the macular edema recurred to some extent in 19 eyes. Compared with initial values, final foveal thickness was reduced significantly in both BRVO and CRVO groups (P < 0.001), but improvement in VA was significant only for eyes with BRVO (P = 0.012). The total number of IVB was 2.8 ± 0.7 for eyes with either BRVO or CRVO. CONCLUSION: Grid photocoagulation combined with IVB has a substantial effect on reducing recurrent macular edema associated with RVO, but the effect on visual acuity is limited. SN - 1177-5483 UR - https://www.unboundmedicine.com/medline/citation/21845030/Grid_photocoagulation_combined_with_intravitreal_bevacizumab_for_recurrent_macular_edema_associated_with_retinal_vein_occlusion_ L2 - https://dx.doi.org/10.2147/OPTH.S22923 DB - PRIME DP - Unbound Medicine ER -
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