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Seroprevalence and correlates of hepatitis a among HIV-negative American men who have sex with men.
Sex Health. 2011 Sep; 8(3):343-8.SH

Abstract

BACKGROUND

Hepatitis A outbreaks are well documented among men who have sex with men (MSM). This analysis examines characteristics associated with hepatitis A virus (HAV) infection among a large group of young adult MSM from five USA cities.

METHODS

The Young Men's Survey was a cross-sectional prevalence study of HIV infection and related behavioural risk factors among MSM aged 15-29 years during 1994-2000. Serum specimens from HIV-negative participants were retrospectively tested for antibodies to HAV (anti-HAV). Data were stratified by ethnicity and analysed with logistic regression.

RESULTS

Overall anti-HAV prevalence was 18.4% among the 2708 participants, and varied by ethnicity from 6.9 to 45.3% and was highest among Hispanic and Asian men (P < 0.001). Prevalence increased with age across all racial/ethnic groups. Among white men, anti-HAV positivity was associated with having 20 or more lifetime male sex partners for those aged 15-22 years (adjusted odds ratio (AOR)=2.1, 95% confidence interval (CI)=1.0-4.1) and ever having had unprotected anal sex for those aged 23-29 years (AOR=2.4, 95% CI=1.2-4.5).

CONCLUSIONS

Factors associated with a history of HAV infection among MSM in non-outbreak settings are probably similar to those among non-MSM. MSM are still at risk for HAV infection as a result of outbreaks occurring in MSM communities. Additional studies of hepatitis A vaccination coverage are needed to determine if strategies to vaccinate MSM are adequate.

Authors+Show Affiliations

Division of Viral Diseases, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30030, USA. Sbialek@cdc.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21851774

Citation

Bialek, Stephanie R., et al. "Seroprevalence and Correlates of Hepatitis a Among HIV-negative American Men Who Have Sex With Men." Sexual Health, vol. 8, no. 3, 2011, pp. 343-8.
Bialek SR, Barry V, Bell BP, et al. Seroprevalence and correlates of hepatitis a among HIV-negative American men who have sex with men. Sex Health. 2011;8(3):343-8.
Bialek, S. R., Barry, V., Bell, B. P., Valleroy, L. A., Behel, S., Mackellar, D. A., Secura, G., Thiede, H., McFarland, W., Ford, W. L., Bingham, T. A., Shehan, D. A., & Celentano, D. D. (2011). Seroprevalence and correlates of hepatitis a among HIV-negative American men who have sex with men. Sexual Health, 8(3), 343-8. https://doi.org/10.1071/SH10162
Bialek SR, et al. Seroprevalence and Correlates of Hepatitis a Among HIV-negative American Men Who Have Sex With Men. Sex Health. 2011;8(3):343-8. PubMed PMID: 21851774.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seroprevalence and correlates of hepatitis a among HIV-negative American men who have sex with men. AU - Bialek,Stephanie R, AU - Barry,Vaughn, AU - Bell,Beth P, AU - Valleroy,Linda A, AU - Behel,Stephanie, AU - Mackellar,Duncan A, AU - Secura,Gina, AU - Thiede,Hanne, AU - McFarland,Willi, AU - Ford,Wesley L, AU - Bingham,Trista A, AU - Shehan,Douglas A, AU - Celentano,David D, PY - 2010/12/14/received PY - 2011/03/11/accepted PY - 2011/8/20/entrez PY - 2011/8/20/pubmed PY - 2011/11/2/medline SP - 343 EP - 8 JF - Sexual health JO - Sex Health VL - 8 IS - 3 N2 - BACKGROUND: Hepatitis A outbreaks are well documented among men who have sex with men (MSM). This analysis examines characteristics associated with hepatitis A virus (HAV) infection among a large group of young adult MSM from five USA cities. METHODS: The Young Men's Survey was a cross-sectional prevalence study of HIV infection and related behavioural risk factors among MSM aged 15-29 years during 1994-2000. Serum specimens from HIV-negative participants were retrospectively tested for antibodies to HAV (anti-HAV). Data were stratified by ethnicity and analysed with logistic regression. RESULTS: Overall anti-HAV prevalence was 18.4% among the 2708 participants, and varied by ethnicity from 6.9 to 45.3% and was highest among Hispanic and Asian men (P < 0.001). Prevalence increased with age across all racial/ethnic groups. Among white men, anti-HAV positivity was associated with having 20 or more lifetime male sex partners for those aged 15-22 years (adjusted odds ratio (AOR)=2.1, 95% confidence interval (CI)=1.0-4.1) and ever having had unprotected anal sex for those aged 23-29 years (AOR=2.4, 95% CI=1.2-4.5). CONCLUSIONS: Factors associated with a history of HAV infection among MSM in non-outbreak settings are probably similar to those among non-MSM. MSM are still at risk for HAV infection as a result of outbreaks occurring in MSM communities. Additional studies of hepatitis A vaccination coverage are needed to determine if strategies to vaccinate MSM are adequate. SN - 1448-5028 UR - https://www.unboundmedicine.com/medline/citation/21851774/Seroprevalence_and_correlates_of_hepatitis_a_among_HIV_negative_American_men_who_have_sex_with_men_ L2 - http://www.publish.csiro.au/journals/abstractHTML.cfm?J=SH&amp;V=8&amp;I=3&amp;F=SH10162abs.XML DB - PRIME DP - Unbound Medicine ER -