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Impact of obesity on cardiovascular disease.

Abstract

Obesity promotes a cascade of secondary pathologies including diabetes, insulin resistance, dyslipidemia, inflammation, thrombosis, hypertension, the metabolic syndrome, and OSA, which collectively heighten the risk for cardiovascular disease. Obesity may also be an independent moderator of cardiac risk apart from these comorbid conditions. Rates of obesity and cardiac disease continue to rise in a parallel and exponential manner. Because obesity is potentially one of the most modifiable mediators of cardiovascular morbidity and mortality, effective treatment and prevention interventions should have a profound and favorable impact on public health.

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  • Authors+Show Affiliations

    ,

    Division of Nutrition and Preventative Medicine, Department of Medicine, William Beaumont Hospital, 4949 Coolidge Highway, Royal Oak, MI 48073, USA. kzalesin@beaumont.edu

    , , ,

    Source

    The Medical clinics of North America 95:5 2011 Sep pg 919-37

    MeSH

    Adolescent
    Body Mass Index
    Body Weights and Measures
    Cardiovascular Diseases
    Child
    Diabetes Mellitus
    Dyslipidemias
    Humans
    Metabolic Syndrome
    Obesity
    Overweight
    Risk Factors

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    21855700

    Citation

    Zalesin, Kerstyn C., et al. "Impact of Obesity On Cardiovascular Disease." The Medical Clinics of North America, vol. 95, no. 5, 2011, pp. 919-37.
    Zalesin KC, Franklin BA, Miller WM, et al. Impact of obesity on cardiovascular disease. Med Clin North Am. 2011;95(5):919-37.
    Zalesin, K. C., Franklin, B. A., Miller, W. M., Peterson, E. D., & McCullough, P. A. (2011). Impact of obesity on cardiovascular disease. The Medical Clinics of North America, 95(5), pp. 919-37. doi:10.1016/j.mcna.2011.06.005.
    Zalesin KC, et al. Impact of Obesity On Cardiovascular Disease. Med Clin North Am. 2011;95(5):919-37. PubMed PMID: 21855700.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Impact of obesity on cardiovascular disease. AU - Zalesin,Kerstyn C, AU - Franklin,Barry A, AU - Miller,Wendy M, AU - Peterson,Eric D, AU - McCullough,Peter A, PY - 2011/8/23/entrez PY - 2011/8/23/pubmed PY - 2011/10/18/medline SP - 919 EP - 37 JF - The Medical clinics of North America JO - Med. Clin. North Am. VL - 95 IS - 5 N2 - Obesity promotes a cascade of secondary pathologies including diabetes, insulin resistance, dyslipidemia, inflammation, thrombosis, hypertension, the metabolic syndrome, and OSA, which collectively heighten the risk for cardiovascular disease. Obesity may also be an independent moderator of cardiac risk apart from these comorbid conditions. Rates of obesity and cardiac disease continue to rise in a parallel and exponential manner. Because obesity is potentially one of the most modifiable mediators of cardiovascular morbidity and mortality, effective treatment and prevention interventions should have a profound and favorable impact on public health. SN - 1557-9859 UR - https://www.unboundmedicine.com/medline/citation/21855700/Impact_of_obesity_on_cardiovascular_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0025-7125(11)00063-0 DB - PRIME DP - Unbound Medicine ER -