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Excessive nocturnal urine production is a major contributing factor to the etiology of nocturia.
J Urol. 2011 Oct; 186(4):1358-63.JU

Abstract

PURPOSE

Nocturnal polyuria is a common but often overlooked cause of nocturia. We investigated the proportion of adults with 2 or greater voids nightly who had nocturnal polyuria in 2 cohorts from the United States and Europe.

MATERIALS AND METHODS

Data on nocturnal polyuria were obtained from 3 or 7-day frequency-volume charts completed by patients as part of screening for inclusion in subsequent trials of nocturia therapy. Patients recorded the time and volume of each void. Nocturnal polyuria was defined as nocturnal urine volume greater than 33% of 24-hour volume, including the first morning void.

RESULTS

In the first cohort 1,003 patients were screened, of whom 846 provided evaluable diary data, including 641 (76%) with nocturnal polyuria. Of the total screened population of 1,003 patients 641 (64%) had confirmed nocturnal polyuria. The prevalence of nocturnal polyuria increased with age but was high in all age groups. In the second cohort 1,412 patients were screened, of whom 917 provided evaluable diary data, including 806 (88%) with nocturnal polyuria. Of the total screened population of 1,412 patients 806 (57%) had confirmed nocturnal polyuria. The prevalence of nocturnal polyuria increased with age but was high in all age groups. Of 158 patients receiving benign prostatic hyperplasia and/or overactive bladder medication 141 (89%) had nocturnal polyuria. In each cohort the nocturnal polyuria prevalence was high in all ethnic groups (63% or greater).

CONCLUSIONS

In this large study nocturnal polyuria was present in most patients with nocturia regardless of gender, age, ethnicity, country and concomitant benign prostatic hyperplasia/overactive bladder therapy.

Authors+Show Affiliations

Department of Urology, State University of New York Downstate Medical School, Brooklyn, New York, USA. urojock@aol.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21855948

Citation

Weiss, Jeffrey P., et al. "Excessive Nocturnal Urine Production Is a Major Contributing Factor to the Etiology of Nocturia." The Journal of Urology, vol. 186, no. 4, 2011, pp. 1358-63.
Weiss JP, van Kerrebroeck PE, Klein BM, et al. Excessive nocturnal urine production is a major contributing factor to the etiology of nocturia. J Urol. 2011;186(4):1358-63.
Weiss, J. P., van Kerrebroeck, P. E., Klein, B. M., & Nørgaard, J. P. (2011). Excessive nocturnal urine production is a major contributing factor to the etiology of nocturia. The Journal of Urology, 186(4), 1358-63. https://doi.org/10.1016/j.juro.2011.05.083
Weiss JP, et al. Excessive Nocturnal Urine Production Is a Major Contributing Factor to the Etiology of Nocturia. J Urol. 2011;186(4):1358-63. PubMed PMID: 21855948.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Excessive nocturnal urine production is a major contributing factor to the etiology of nocturia. AU - Weiss,Jeffrey P, AU - van Kerrebroeck,Philip E V, AU - Klein,Bjarke M, AU - Nørgaard,Jens Peter, PY - 2011/02/18/received PY - 2011/8/23/entrez PY - 2011/8/23/pubmed PY - 2011/11/9/medline SP - 1358 EP - 63 JF - The Journal of urology JO - J Urol VL - 186 IS - 4 N2 - PURPOSE: Nocturnal polyuria is a common but often overlooked cause of nocturia. We investigated the proportion of adults with 2 or greater voids nightly who had nocturnal polyuria in 2 cohorts from the United States and Europe. MATERIALS AND METHODS: Data on nocturnal polyuria were obtained from 3 or 7-day frequency-volume charts completed by patients as part of screening for inclusion in subsequent trials of nocturia therapy. Patients recorded the time and volume of each void. Nocturnal polyuria was defined as nocturnal urine volume greater than 33% of 24-hour volume, including the first morning void. RESULTS: In the first cohort 1,003 patients were screened, of whom 846 provided evaluable diary data, including 641 (76%) with nocturnal polyuria. Of the total screened population of 1,003 patients 641 (64%) had confirmed nocturnal polyuria. The prevalence of nocturnal polyuria increased with age but was high in all age groups. In the second cohort 1,412 patients were screened, of whom 917 provided evaluable diary data, including 806 (88%) with nocturnal polyuria. Of the total screened population of 1,412 patients 806 (57%) had confirmed nocturnal polyuria. The prevalence of nocturnal polyuria increased with age but was high in all age groups. Of 158 patients receiving benign prostatic hyperplasia and/or overactive bladder medication 141 (89%) had nocturnal polyuria. In each cohort the nocturnal polyuria prevalence was high in all ethnic groups (63% or greater). CONCLUSIONS: In this large study nocturnal polyuria was present in most patients with nocturia regardless of gender, age, ethnicity, country and concomitant benign prostatic hyperplasia/overactive bladder therapy. SN - 1527-3792 UR - https://www.unboundmedicine.com/medline/citation/21855948/Excessive_nocturnal_urine_production_is_a_major_contributing_factor_to_the_etiology_of_nocturia_ DB - PRIME DP - Unbound Medicine ER -