Tags

Type your tag names separated by a space and hit enter

Acute resistance exercise augments integrative myofibrillar protein synthesis.
Metabolism. 2012 Feb; 61(2):153-6.M

Abstract

The purpose of this study was to determine whether an acute bout of high-intensity resistance exercise (RE) would augment integrative mixed muscle and myofibrillar protein fractional synthesis rates (FSRs) when total energy and macronutrient intake was controlled. Twelve healthy young men were studied over 24 hours and performed an acute bout of exhaustive (5 sets until volitional failure of their 85% 1-repetition maximum) unilateral leg press and knee extension exercise, such that one leg was exercised (EX) and the other served as a control (CON). (2)H(2)O (70%) was provided to measure mixed muscle and myofibrillar FSR, and muscle biopsies (vastus lateralis) were collected from the EX and CON legs 16 hours following the RE session. (2)H-labeling of body water over the course of the experiment was 0.32 ± 0.01 mole percent excess. Interestingly, integrative mixed muscle FSR (percent per hour) was similar between the CON (0.76% ± 0.08%) and EX (0.69% ± 0.06%) legs. In contrast, upon determination of myofibrillar FSR, there was an RE effect (EX, 0.94% ± 0.16% vs CON, 0.75% ± 0.08%; P < .05). High-intensity RE without prior training impacts integrative myofibrillar 24-hour FSR, perhaps without altering total responses.

Authors+Show Affiliations

Department of Health and Kinesiology, Texas A&M University, College Station, TX 77843, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Controlled Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21864869

Citation

Gasier, Heath G., et al. "Acute Resistance Exercise Augments Integrative Myofibrillar Protein Synthesis." Metabolism: Clinical and Experimental, vol. 61, no. 2, 2012, pp. 153-6.
Gasier HG, Fluckey JD, Previs SF, et al. Acute resistance exercise augments integrative myofibrillar protein synthesis. Metabolism. 2012;61(2):153-6.
Gasier, H. G., Fluckey, J. D., Previs, S. F., Wiggs, M. P., & Riechman, S. E. (2012). Acute resistance exercise augments integrative myofibrillar protein synthesis. Metabolism: Clinical and Experimental, 61(2), 153-6. https://doi.org/10.1016/j.metabol.2011.07.001
Gasier HG, et al. Acute Resistance Exercise Augments Integrative Myofibrillar Protein Synthesis. Metabolism. 2012;61(2):153-6. PubMed PMID: 21864869.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute resistance exercise augments integrative myofibrillar protein synthesis. AU - Gasier,Heath G, AU - Fluckey,James D, AU - Previs,Stephen F, AU - Wiggs,Michael P, AU - Riechman,Steven E, Y1 - 2011/08/23/ PY - 2011/03/25/received PY - 2011/06/24/revised PY - 2011/07/03/accepted PY - 2011/8/26/entrez PY - 2011/8/26/pubmed PY - 2012/3/21/medline SP - 153 EP - 6 JF - Metabolism: clinical and experimental JO - Metabolism VL - 61 IS - 2 N2 - The purpose of this study was to determine whether an acute bout of high-intensity resistance exercise (RE) would augment integrative mixed muscle and myofibrillar protein fractional synthesis rates (FSRs) when total energy and macronutrient intake was controlled. Twelve healthy young men were studied over 24 hours and performed an acute bout of exhaustive (5 sets until volitional failure of their 85% 1-repetition maximum) unilateral leg press and knee extension exercise, such that one leg was exercised (EX) and the other served as a control (CON). (2)H(2)O (70%) was provided to measure mixed muscle and myofibrillar FSR, and muscle biopsies (vastus lateralis) were collected from the EX and CON legs 16 hours following the RE session. (2)H-labeling of body water over the course of the experiment was 0.32 ± 0.01 mole percent excess. Interestingly, integrative mixed muscle FSR (percent per hour) was similar between the CON (0.76% ± 0.08%) and EX (0.69% ± 0.06%) legs. In contrast, upon determination of myofibrillar FSR, there was an RE effect (EX, 0.94% ± 0.16% vs CON, 0.75% ± 0.08%; P < .05). High-intensity RE without prior training impacts integrative myofibrillar 24-hour FSR, perhaps without altering total responses. SN - 1532-8600 UR - https://www.unboundmedicine.com/medline/citation/21864869/Acute_resistance_exercise_augments_integrative_myofibrillar_protein_synthesis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0026-0495(11)00217-4 DB - PRIME DP - Unbound Medicine ER -