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Microbial metabolism. Part 13. Metabolites of hesperetin.
Bioorg Med Chem Lett. 2011 Oct 01; 21(19):5784-6.BM

Abstract

The fungal culture, Mucor ramannianus (ATCC 2628) transformed hesperitin (1) to four metabolites: 4'-methoxy-5,7,8,3'-tetrahydroxyflavanone (8-hydroxyhesperetin) (2), 5,7,3',4'-tetrahydroxyflavanone (eriodictyol) (3), 4'-methoxy-5,3'-dihydroxyflavanone 7-sulfate (hesperetin 7-sulfate) (4) and 5,7,3'-trihydroxyflavanone 4'-O-α-quinovopyranoside (eriodictyol 4'-O-α-quinovopyranoside) (5). The structures were established by spectroscopic methods.

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Authors+Show Affiliations

Herath W
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
Khan IA
No affiliation info available

MeSH

Antineoplastic AgentsAntioxidantsDrug Screening Assays, AntitumorFermentationFlavanonesHesperidinMolecular StructureMucor

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

21873058

Citation

Herath, Wimal, and Ikhlas Ahmad Khan. "Microbial Metabolism. Part 13. Metabolites of Hesperetin." Bioorganic & Medicinal Chemistry Letters, vol. 21, no. 19, 2011, pp. 5784-6.
Herath W, Khan IA. Microbial metabolism. Part 13. Metabolites of hesperetin. Bioorg Med Chem Lett. 2011;21(19):5784-6.
Herath, W., & Khan, I. A. (2011). Microbial metabolism. Part 13. Metabolites of hesperetin. Bioorganic & Medicinal Chemistry Letters, 21(19), 5784-6. https://doi.org/10.1016/j.bmcl.2011.08.004
Herath W, Khan IA. Microbial Metabolism. Part 13. Metabolites of Hesperetin. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5784-6. PubMed PMID: 21873058.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Microbial metabolism. Part 13. Metabolites of hesperetin. AU - Herath,Wimal, AU - Khan,Ikhlas Ahmad, Y1 - 2011/08/09/ PY - 2011/06/02/received PY - 2011/07/29/revised PY - 2011/08/01/accepted PY - 2011/8/30/entrez PY - 2011/8/30/pubmed PY - 2012/4/17/medline SP - 5784 EP - 6 JF - Bioorganic & medicinal chemistry letters JO - Bioorg Med Chem Lett VL - 21 IS - 19 N2 - The fungal culture, Mucor ramannianus (ATCC 2628) transformed hesperitin (1) to four metabolites: 4'-methoxy-5,7,8,3'-tetrahydroxyflavanone (8-hydroxyhesperetin) (2), 5,7,3',4'-tetrahydroxyflavanone (eriodictyol) (3), 4'-methoxy-5,3'-dihydroxyflavanone 7-sulfate (hesperetin 7-sulfate) (4) and 5,7,3'-trihydroxyflavanone 4'-O-α-quinovopyranoside (eriodictyol 4'-O-α-quinovopyranoside) (5). The structures were established by spectroscopic methods. SN - 1464-3405 UR - https://www.unboundmedicine.com/medline/citation/21873058/Microbial_metabolism__Part_13__Metabolites_of_hesperetin_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0960-894X(11)01075-4 DB - PRIME DP - Unbound Medicine ER -