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Significant correlation between visual acuity and recovery of foveal cone microstructures after macular hole surgery.
Am J Ophthalmol. 2012 Jan; 153(1):111-9.e1.AJ

Abstract

PURPOSE

To determine whether a recovery of the microstructures of the foveal photoreceptors after macular hole closure is correlated with best-corrected visual acuity (BCVA).

DESIGN

Retrospective, consecutive, observational case series.

SETTING

Single-center academic practice.

STUDY POPULATION

Forty-one eyes of 41 patients with surgically closed macular holes. OBSERVATIONAL PROCEDURES: The presence and intactness of the cone outer segment tips (COST) line were determined by spectral-domain optical coherence tomography and compared with the presence of the inner segment/outer segment (IS/OS) junction and the external limiting membrane (ELM) at 1, 3, 6, 9, and 12 months after the macular hole surgery.

MAIN OUTCOME MEASURE

The correlation between the integrity of the foveal photoreceptor microstructures and the BCVA.

RESULTS

A distinct COST line was first seen at 6 months after the surgery. A distinct or irregular COST line was observed only in eyes with an intact IS/OS junction and ELM. Eyes with a distinct or irregular COST line had significantly better BCVA than those with a disrupted COST line in eyes with an intact IS/OS junction and ELM at 12 months (P = .030). The BCVA was ≥20/25 at 12 months in 91% of the eyes with a distinct or irregular COST line but in only 44% of the eyes without a COST line (P = .015).

CONCLUSIONS

The significant correlation between the BCVA and a distinct or irregular COST line after successful macular hole surgery indicates that the recovery of foveal cone microstructure is associated with good postoperative BCVA.

Authors+Show Affiliations

Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21880295

Citation

Itoh, Yuji, et al. "Significant Correlation Between Visual Acuity and Recovery of Foveal Cone Microstructures After Macular Hole Surgery." American Journal of Ophthalmology, vol. 153, no. 1, 2012, pp. 111-9.e1.
Itoh Y, Inoue M, Rii T, et al. Significant correlation between visual acuity and recovery of foveal cone microstructures after macular hole surgery. Am J Ophthalmol. 2012;153(1):111-9.e1.
Itoh, Y., Inoue, M., Rii, T., Hiraoka, T., & Hirakata, A. (2012). Significant correlation between visual acuity and recovery of foveal cone microstructures after macular hole surgery. American Journal of Ophthalmology, 153(1), 111-e1. https://doi.org/10.1016/j.ajo.2011.05.039
Itoh Y, et al. Significant Correlation Between Visual Acuity and Recovery of Foveal Cone Microstructures After Macular Hole Surgery. Am J Ophthalmol. 2012;153(1):111-9.e1. PubMed PMID: 21880295.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Significant correlation between visual acuity and recovery of foveal cone microstructures after macular hole surgery. AU - Itoh,Yuji, AU - Inoue,Makoto, AU - Rii,Tosho, AU - Hiraoka,Tomoyuki, AU - Hirakata,Akito, Y1 - 2011/08/30/ PY - 2011/01/10/received PY - 2011/05/17/revised PY - 2011/05/20/accepted PY - 2011/9/2/entrez PY - 2011/9/2/pubmed PY - 2012/2/2/medline SP - 111 EP - 9.e1 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 153 IS - 1 N2 - PURPOSE: To determine whether a recovery of the microstructures of the foveal photoreceptors after macular hole closure is correlated with best-corrected visual acuity (BCVA). DESIGN: Retrospective, consecutive, observational case series. SETTING: Single-center academic practice. STUDY POPULATION: Forty-one eyes of 41 patients with surgically closed macular holes. OBSERVATIONAL PROCEDURES: The presence and intactness of the cone outer segment tips (COST) line were determined by spectral-domain optical coherence tomography and compared with the presence of the inner segment/outer segment (IS/OS) junction and the external limiting membrane (ELM) at 1, 3, 6, 9, and 12 months after the macular hole surgery. MAIN OUTCOME MEASURE: The correlation between the integrity of the foveal photoreceptor microstructures and the BCVA. RESULTS: A distinct COST line was first seen at 6 months after the surgery. A distinct or irregular COST line was observed only in eyes with an intact IS/OS junction and ELM. Eyes with a distinct or irregular COST line had significantly better BCVA than those with a disrupted COST line in eyes with an intact IS/OS junction and ELM at 12 months (P = .030). The BCVA was ≥20/25 at 12 months in 91% of the eyes with a distinct or irregular COST line but in only 44% of the eyes without a COST line (P = .015). CONCLUSIONS: The significant correlation between the BCVA and a distinct or irregular COST line after successful macular hole surgery indicates that the recovery of foveal cone microstructure is associated with good postoperative BCVA. SN - 1879-1891 UR - https://www.unboundmedicine.com/medline/citation/21880295/Significant_correlation_between_visual_acuity_and_recovery_of_foveal_cone_microstructures_after_macular_hole_surgery_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(11)00466-1 DB - PRIME DP - Unbound Medicine ER -