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Divergence with age in blood pressure in African-Caribbean and white populations in England: implications for screening for hypertension.
Am J Hypertens. 2012 Jan; 25(1):89-96.AJ

Abstract

BACKGROUND

We assessed when blood pressure (BP) and hypertension begin to rise in African-Caribbeans compared to the white population; and whether the change relates to body mass index (BMI).

METHODS

Secondary analysis of the cross-sectional Health Surveys for England among 22,723 participants (21,344 whites and 1,379 African-Caribbeans) adults aged ≥18 years.

RESULTS

The cubic spline graphs showed a crossover (African-Caribbean greater than whites) at 30-40 years in BP. Age-specific mean BP and hypertension prevalence data showed at 20-29 years African-Caribbean men were advantaged but not thereafter. There was little difference in BMI in men. African-Caribbean women had lower systolic BP (but higher prevalence of hypertension) at 20-29 years but higher BP and prevalence of hypertension thereafter. African-Caribbean women had higher BMI than white women. Regression showed an age and ethnicity interaction for systolic (0.076 mm Hg greater increase per year, P = 0.054) and diastolic BP (0.068 mm Hg greater increase per year (P = 0.009) and hypertension (OR equals 1.02, P = 0.004) in African-Caribbean men, and diastolic BP in African-Caribbean women (0.057 mm Hg greater increase per year, P = 0.017). Crossover was 28, 44, and 28 years for systolic BP, diastolic BP and hypertension in men, respectively; and 40 years for diastolic BP in women.

CONCLUSIONS

Clinicians should be extra vigilant about screening African-Caribbean patients from the age of 30 years. Detailed study is needed to understand the still mysterious mechanisms for this crossover.

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Authors+Show Affiliations

Agyemang C
Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. c.o.agyemang@amc.uva.nl
Humphry RW
No affiliation info available
Bhopal R
No affiliation info available

MeSH

AdultAfrican Continental Ancestry GroupAge FactorsBlood PressureBlood Pressure DeterminationBody Mass IndexCaribbean RegionEnglandEthnic GroupsEuropean Continental Ancestry GroupFemaleHumansHypertensionMalePrevalence

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21881618

Citation

Agyemang, Charles, et al. "Divergence With Age in Blood Pressure in African-Caribbean and White Populations in England: Implications for Screening for Hypertension." American Journal of Hypertension, vol. 25, no. 1, 2012, pp. 89-96.
Agyemang C, Humphry RW, Bhopal R. Divergence with age in blood pressure in African-Caribbean and white populations in England: implications for screening for hypertension. Am J Hypertens. 2012;25(1):89-96.
Agyemang, C., Humphry, R. W., & Bhopal, R. (2012). Divergence with age in blood pressure in African-Caribbean and white populations in England: implications for screening for hypertension. American Journal of Hypertension, 25(1), 89-96. https://doi.org/10.1038/ajh.2011.160
Agyemang C, Humphry RW, Bhopal R. Divergence With Age in Blood Pressure in African-Caribbean and White Populations in England: Implications for Screening for Hypertension. Am J Hypertens. 2012;25(1):89-96. PubMed PMID: 21881618.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Divergence with age in blood pressure in African-Caribbean and white populations in England: implications for screening for hypertension. AU - Agyemang,Charles, AU - Humphry,Roger W, AU - Bhopal,Raj, Y1 - 2011/09/01/ PY - 2011/9/2/entrez PY - 2011/9/2/pubmed PY - 2012/4/13/medline SP - 89 EP - 96 JF - American journal of hypertension JO - Am J Hypertens VL - 25 IS - 1 N2 - BACKGROUND: We assessed when blood pressure (BP) and hypertension begin to rise in African-Caribbeans compared to the white population; and whether the change relates to body mass index (BMI). METHODS: Secondary analysis of the cross-sectional Health Surveys for England among 22,723 participants (21,344 whites and 1,379 African-Caribbeans) adults aged ≥18 years. RESULTS: The cubic spline graphs showed a crossover (African-Caribbean greater than whites) at 30-40 years in BP. Age-specific mean BP and hypertension prevalence data showed at 20-29 years African-Caribbean men were advantaged but not thereafter. There was little difference in BMI in men. African-Caribbean women had lower systolic BP (but higher prevalence of hypertension) at 20-29 years but higher BP and prevalence of hypertension thereafter. African-Caribbean women had higher BMI than white women. Regression showed an age and ethnicity interaction for systolic (0.076 mm Hg greater increase per year, P = 0.054) and diastolic BP (0.068 mm Hg greater increase per year (P = 0.009) and hypertension (OR equals 1.02, P = 0.004) in African-Caribbean men, and diastolic BP in African-Caribbean women (0.057 mm Hg greater increase per year, P = 0.017). Crossover was 28, 44, and 28 years for systolic BP, diastolic BP and hypertension in men, respectively; and 40 years for diastolic BP in women. CONCLUSIONS: Clinicians should be extra vigilant about screening African-Caribbean patients from the age of 30 years. Detailed study is needed to understand the still mysterious mechanisms for this crossover. SN - 1941-7225 UR - https://www.unboundmedicine.com/medline/citation/21881618/Divergence_with_age_in_blood_pressure_in_African_Caribbean_and_white_populations_in_England:_implications_for_screening_for_hypertension_ L2 - https://academic.oup.com/ajh/article-lookup/doi/10.1038/ajh.2011.160 DB - PRIME DP - Unbound Medicine ER -