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Juvenile arthritis and uveitis.
Surv Ophthalmol. 1990 Jan-Feb; 34(4):253-67.SO

Abstract

The association between juvenile arthritis and uveitis is reviewed. Some children with the HLA-B27 related spondyloarthropathies develop anterior uveitis. About 20% of patients with juvenile rheumatoid arthritis (JRA) who are negative for IgM rheumatoid factor develop a frequently bilateral, nongranulomatous chronic anterior uveitis. Risk factors for uveitis in JRA patients are: female gender, pauciarticular onset of arthritis, presence of circulating antinuclear antibodies, and the antigens HLA-DW5 and HLA-DPw2. Uveitis is rare after seven years or more have elapsed from the onset of arthritis. The visual prognosis in patients with uveitis is good in 25% and fair in 50%. The remaining 25% develop visual impairment from complicated cataract and/or secondary inflammatory glaucoma. The potential benefit of cytotoxic agents in the treatment of intractable uveitis is outweighed by the risk of serious side effects. The management of secondary inflammatory glaucoma is unsatisfactory, but the results of treatment of complicated cataracts by lensectomy-vitrectomy are good.

Authors+Show Affiliations

Prince Charles Eye Unit, King Edward VII Hospital, Windsor, Berkshire, United Kingdom.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

2188388

Citation

Kanski, J J.. "Juvenile Arthritis and Uveitis." Survey of Ophthalmology, vol. 34, no. 4, 1990, pp. 253-67.
Kanski JJ. Juvenile arthritis and uveitis. Surv Ophthalmol. 1990;34(4):253-67.
Kanski, J. J. (1990). Juvenile arthritis and uveitis. Survey of Ophthalmology, 34(4), 253-67.
Kanski JJ. Juvenile Arthritis and Uveitis. Surv Ophthalmol. 1990 Jan-Feb;34(4):253-67. PubMed PMID: 2188388.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Juvenile arthritis and uveitis. A1 - Kanski,J J, PY - 1990/1/1/pubmed PY - 1990/1/1/medline PY - 1990/1/1/entrez SP - 253 EP - 67 JF - Survey of ophthalmology JO - Surv Ophthalmol VL - 34 IS - 4 N2 - The association between juvenile arthritis and uveitis is reviewed. Some children with the HLA-B27 related spondyloarthropathies develop anterior uveitis. About 20% of patients with juvenile rheumatoid arthritis (JRA) who are negative for IgM rheumatoid factor develop a frequently bilateral, nongranulomatous chronic anterior uveitis. Risk factors for uveitis in JRA patients are: female gender, pauciarticular onset of arthritis, presence of circulating antinuclear antibodies, and the antigens HLA-DW5 and HLA-DPw2. Uveitis is rare after seven years or more have elapsed from the onset of arthritis. The visual prognosis in patients with uveitis is good in 25% and fair in 50%. The remaining 25% develop visual impairment from complicated cataract and/or secondary inflammatory glaucoma. The potential benefit of cytotoxic agents in the treatment of intractable uveitis is outweighed by the risk of serious side effects. The management of secondary inflammatory glaucoma is unsatisfactory, but the results of treatment of complicated cataracts by lensectomy-vitrectomy are good. SN - 0039-6257 UR - https://www.unboundmedicine.com/medline/citation/2188388/Juvenile_arthritis_and_uveitis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0039-6257(90)90026-R DB - PRIME DP - Unbound Medicine ER -