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Surgical management of large juvenile nasopharyngeal angiofibroma invading the infratemporal fossa with intracranial extradural parasellar involvement in an 8-year-old boy.
Auris Nasus Larynx 2012; 39(3):341-4AN

Abstract

We present a rare case of a large juvenile nasopharyngeal angiofibroma (JNA) in an 8-year-old boy. Preoperative imaging revealed that the tumor had widely extended to the sphenoid sinus, infratemporal fossa, and cavernous sinus. Following embolization of the feeding vessels, the tumor was successfully removed by a combination of an orbitozygomatic approach and Le Fort I osteotomy under frontolateral craniotomy. An endoscope assisted in the surgery. At 15 months follow-up, the patient was free of the disease with no facial palsy, scars, or malocclusion. JNA is a benign tumor that typically affects adolescent males and is rarely observed during prepuberty. Complete removal of JNA by surgery, the initial therapy, is generally required. However, as in the present case, a large JNA with wide extension requires extended surgery, and such a surgery is more invasive for prepubertal patients. Using an appropriate combination of surgical approaches, a large JNA developed during prepuberty can be safely removed with reduced morbidity.

Authors+Show Affiliations

Department of Otolaryngology, Tokyo Medical and Dental University, Japan.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21885225

Citation

Yamada, Masato, et al. "Surgical Management of Large Juvenile Nasopharyngeal Angiofibroma Invading the Infratemporal Fossa With Intracranial Extradural Parasellar Involvement in an 8-year-old Boy." Auris, Nasus, Larynx, vol. 39, no. 3, 2012, pp. 341-4.
Yamada M, Tsunoda A, Hagino K, et al. Surgical management of large juvenile nasopharyngeal angiofibroma invading the infratemporal fossa with intracranial extradural parasellar involvement in an 8-year-old boy. Auris Nasus Larynx. 2012;39(3):341-4.
Yamada, M., Tsunoda, A., Hagino, K., Aoyagi, M., Kawano, Y., Yano, T., ... Kishimoto, S. (2012). Surgical management of large juvenile nasopharyngeal angiofibroma invading the infratemporal fossa with intracranial extradural parasellar involvement in an 8-year-old boy. Auris, Nasus, Larynx, 39(3), pp. 341-4. doi:10.1016/j.anl.2011.07.017.
Yamada M, et al. Surgical Management of Large Juvenile Nasopharyngeal Angiofibroma Invading the Infratemporal Fossa With Intracranial Extradural Parasellar Involvement in an 8-year-old Boy. Auris Nasus Larynx. 2012;39(3):341-4. PubMed PMID: 21885225.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Surgical management of large juvenile nasopharyngeal angiofibroma invading the infratemporal fossa with intracranial extradural parasellar involvement in an 8-year-old boy. AU - Yamada,Masato, AU - Tsunoda,Atsunobu, AU - Hagino,Koji, AU - Aoyagi,Masaru, AU - Kawano,Yoshihisa, AU - Yano,Tomoyuki, AU - Tanaka,Kentaro, AU - Kishimoto,Seiji, Y1 - 2011/08/31/ PY - 2011/03/19/received PY - 2011/07/28/revised PY - 2011/07/29/accepted PY - 2011/9/3/entrez PY - 2011/9/3/pubmed PY - 2012/8/17/medline SP - 341 EP - 4 JF - Auris, nasus, larynx JO - Auris Nasus Larynx VL - 39 IS - 3 N2 - We present a rare case of a large juvenile nasopharyngeal angiofibroma (JNA) in an 8-year-old boy. Preoperative imaging revealed that the tumor had widely extended to the sphenoid sinus, infratemporal fossa, and cavernous sinus. Following embolization of the feeding vessels, the tumor was successfully removed by a combination of an orbitozygomatic approach and Le Fort I osteotomy under frontolateral craniotomy. An endoscope assisted in the surgery. At 15 months follow-up, the patient was free of the disease with no facial palsy, scars, or malocclusion. JNA is a benign tumor that typically affects adolescent males and is rarely observed during prepuberty. Complete removal of JNA by surgery, the initial therapy, is generally required. However, as in the present case, a large JNA with wide extension requires extended surgery, and such a surgery is more invasive for prepubertal patients. Using an appropriate combination of surgical approaches, a large JNA developed during prepuberty can be safely removed with reduced morbidity. SN - 1879-1476 UR - https://www.unboundmedicine.com/medline/citation/21885225/Surgical_management_of_large_juvenile_nasopharyngeal_angiofibroma_invading_the_infratemporal_fossa_with_intracranial_extradural_parasellar_involvement_in_an_8_year_old_boy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0385-8146(11)00206-9 DB - PRIME DP - Unbound Medicine ER -