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Evaluation of intralesional propranolol for periocular capillary hemangioma.
Clin Ophthalmol 2011; 5:1135-40CO

Abstract

BACKGROUND

The purpose of this study was to evaluate the use of intralesional propranolol injection in the management of periocular capillary hemangioma.

METHODS

A prospective study was performed in 22 consecutive patients with periocular hemangioma. Twelve patients underwent intralesional propranolol injection and ten patients underwent intralesional triamcinolone injection. The size of the lesion was measured serially every week during the first month, every 2 weeks for the second month, and then monthly for another 2 months. The refractive error and degree of ptosis if present were measured before injection and at the end of the study.

RESULTS

There was reduction in the size of hemangioma, astigmatic error, and degree of ptosis in both groups. The difference in outcome between both groups was not statistically significant. Rebound growth occurred in 25% of the propranolol group and 30% of the steroid group but responded to reinjection. No adverse effects were reported during or after intralesional propranolol injection.

CONCLUSION

Intralesional propranolol injection is an alternative and effective method for treatment of infantile periocular hemangioma.

Authors+Show Affiliations

Cairo University Faculty of Medicine, Cairo, Egypt.No affiliation info available

Pub Type(s)

Case Reports

Language

eng

PubMed ID

21887095

Citation

Awadein, Ahmed, and Mohamed A. Fakhry. "Evaluation of Intralesional Propranolol for Periocular Capillary Hemangioma." Clinical Ophthalmology (Auckland, N.Z.), vol. 5, 2011, pp. 1135-40.
Awadein A, Fakhry MA. Evaluation of intralesional propranolol for periocular capillary hemangioma. Clin Ophthalmol. 2011;5:1135-40.
Awadein, A., & Fakhry, M. A. (2011). Evaluation of intralesional propranolol for periocular capillary hemangioma. Clinical Ophthalmology (Auckland, N.Z.), 5, pp. 1135-40. doi:10.2147/OPTH.S22909.
Awadein A, Fakhry MA. Evaluation of Intralesional Propranolol for Periocular Capillary Hemangioma. Clin Ophthalmol. 2011;5:1135-40. PubMed PMID: 21887095.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of intralesional propranolol for periocular capillary hemangioma. AU - Awadein,Ahmed, AU - Fakhry,Mohamed A, Y1 - 2011/08/15/ PY - 2011/08/12/received PY - 2011/9/3/entrez PY - 2011/9/3/pubmed PY - 2011/9/3/medline KW - intralesional KW - periocular capillary hemangioma KW - propranolol SP - 1135 EP - 40 JF - Clinical ophthalmology (Auckland, N.Z.) JO - Clin Ophthalmol VL - 5 N2 - BACKGROUND: The purpose of this study was to evaluate the use of intralesional propranolol injection in the management of periocular capillary hemangioma. METHODS: A prospective study was performed in 22 consecutive patients with periocular hemangioma. Twelve patients underwent intralesional propranolol injection and ten patients underwent intralesional triamcinolone injection. The size of the lesion was measured serially every week during the first month, every 2 weeks for the second month, and then monthly for another 2 months. The refractive error and degree of ptosis if present were measured before injection and at the end of the study. RESULTS: There was reduction in the size of hemangioma, astigmatic error, and degree of ptosis in both groups. The difference in outcome between both groups was not statistically significant. Rebound growth occurred in 25% of the propranolol group and 30% of the steroid group but responded to reinjection. No adverse effects were reported during or after intralesional propranolol injection. CONCLUSION: Intralesional propranolol injection is an alternative and effective method for treatment of infantile periocular hemangioma. SN - 1177-5483 UR - https://www.unboundmedicine.com/medline/citation/21887095/Evaluation_of_intralesional_propranolol_for_periocular_capillary_hemangioma_ L2 - https://dx.doi.org/10.2147/OPTH.S22909 DB - PRIME DP - Unbound Medicine ER -