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A new biphenyl and antimicrobial activity of extracts and compounds from Clusia burlemarxii.
Fitoterapia. 2011 Dec; 82(8):1237-40.F

Abstract

Phytochemical investigation on Clusia burlemarxii (Clusiaceae) led to isolation and identification of nine compounds. Were isolated from leaves 3-O-α-L- rhamnopyranosylquercetin, 3-O-α-L-rhamnopyranosylkaempferol, 4-hydroxy-5,5-dimethyldihydrofuran-2-one, 2Z-δ-tocotrienoloic acid and friedelin and were isolated from trunk betulinic acid, protocatechuic acid, lyoniresinol, and a new biphenyl 2,2-dimethyl-3,5-dihydroxy-7-(4-hydroxyphenyl)chromane. The structures were determined by ¹H, ¹³C-NMR, DEPT, HMBC, HMQC, HRESIMS. The Minimal Inhibitory Concentration against Streptococcus mutans, Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus, Escherichia coli, Salmonella choleraesuis, Pseudomonas aeruginosa, Aspergillus niger and Cladosporium cladosporioides was also determined. Extracts and compounds showed significant activity against tested Gram-positive bacteria, none activity against tested Gram-negative bacteria and fungi.

Authors+Show Affiliations

Grupo de Estudos de Substâncias Naturais Orgânicas (GESNAT), Instituto de Química, Universidade Federal da Bahia, Campus Universitário de Ondina, 40170-290, Salvador, Bahia, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21893172

Citation

Ribeiro, Paulo R., et al. "A New Biphenyl and Antimicrobial Activity of Extracts and Compounds From Clusia Burlemarxii." Fitoterapia, vol. 82, no. 8, 2011, pp. 1237-40.
Ribeiro PR, Ferraz CG, Guedes ML, et al. A new biphenyl and antimicrobial activity of extracts and compounds from Clusia burlemarxii. Fitoterapia. 2011;82(8):1237-40.
Ribeiro, P. R., Ferraz, C. G., Guedes, M. L., Martins, D., & Cruz, F. G. (2011). A new biphenyl and antimicrobial activity of extracts and compounds from Clusia burlemarxii. Fitoterapia, 82(8), 1237-40. https://doi.org/10.1016/j.fitote.2011.08.012
Ribeiro PR, et al. A New Biphenyl and Antimicrobial Activity of Extracts and Compounds From Clusia Burlemarxii. Fitoterapia. 2011;82(8):1237-40. PubMed PMID: 21893172.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new biphenyl and antimicrobial activity of extracts and compounds from Clusia burlemarxii. AU - Ribeiro,Paulo R, AU - Ferraz,Caline G, AU - Guedes,Maria L S, AU - Martins,Dirceu, AU - Cruz,Frederico G, Y1 - 2011/08/27/ PY - 2011/01/19/received PY - 2011/08/16/revised PY - 2011/08/17/accepted PY - 2011/9/7/entrez PY - 2011/9/7/pubmed PY - 2012/4/26/medline SP - 1237 EP - 40 JF - Fitoterapia JO - Fitoterapia VL - 82 IS - 8 N2 - Phytochemical investigation on Clusia burlemarxii (Clusiaceae) led to isolation and identification of nine compounds. Were isolated from leaves 3-O-α-L- rhamnopyranosylquercetin, 3-O-α-L-rhamnopyranosylkaempferol, 4-hydroxy-5,5-dimethyldihydrofuran-2-one, 2Z-δ-tocotrienoloic acid and friedelin and were isolated from trunk betulinic acid, protocatechuic acid, lyoniresinol, and a new biphenyl 2,2-dimethyl-3,5-dihydroxy-7-(4-hydroxyphenyl)chromane. The structures were determined by ¹H, ¹³C-NMR, DEPT, HMBC, HMQC, HRESIMS. The Minimal Inhibitory Concentration against Streptococcus mutans, Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus, Escherichia coli, Salmonella choleraesuis, Pseudomonas aeruginosa, Aspergillus niger and Cladosporium cladosporioides was also determined. Extracts and compounds showed significant activity against tested Gram-positive bacteria, none activity against tested Gram-negative bacteria and fungi. SN - 1873-6971 UR - https://www.unboundmedicine.com/medline/citation/21893172/A_new_biphenyl_and_antimicrobial_activity_of_extracts_and_compounds_from_Clusia_burlemarxii_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0367-326X(11)00212-7 DB - PRIME DP - Unbound Medicine ER -