Tags

Type your tag names separated by a space and hit enter

Depression scores associate with chronotype and social jetlag in a rural population.
Chronobiol Int. 2011 Nov; 28(9):771-8.CI

Abstract

In public health, mood disorders are among the most important mental impairments. Patients with depressive episodes exhibit daily mood variations, abnormal patterns in sleep-wake behavior, and in the daily rhythms of several endocrine-metabolic parameters. Although the relationship between the sleep/circadian processes and mood disorders is poorly understood, clock-related therapies, such as light therapy, sleep deprivation, and rigid sleep schedules, have been shown to be effective treatments. Several studies investigated the relationship between circadian phenotype (chronotype) and depression. These focused mainly on urban populations and assessed diurnal preferences (Morningness-Eveningness score) rather than the actual timing of sleep and activity. Here, we used the Beck Depression Inventory (BDI) in an essentially rural population (N?=?4051), and investigated its relation to circadian phenotype (chronotype and social jetlag), assessed with the Munich Chronotype Questionnaire (MCTQ). In our study design, we (i) normalized both chronotype and BDI scores for age and sex (MSF(sas) and BDI(as), respectively); (ii) calculated individual social jetlag (misalignment of the biological and social time); and (iii) investigated the relationship between circadian phenotypes and BDI scores in a population homogeneous in respect to culture, socioeconomic factors, and daily light exposure. A 15.65% (N?=?634) of the participants showed mild to severe depressive BDI scores. Late chronotypes had a higher BDI(as) than intermediate and early types, which was independent of whether or not the participants were smokers. Both chronotype and BDI(as) correlated positively with social jetlag. BDI(as) was significantly higher in subjects with >2?h of social jetlag than in the rest of the population?again independent of smoking status. We also compared chronotype and social jetlag distributions between BDI categories (no symptoms, minimal symptoms, and mild to severe symptoms of depression) separately for men and women and for four age groups; specifically in the age group 31?40 yrs, subjects with mild to severe BDI scores were significantly later chronotypes and suffered from higher social jetlag. Our results indicate that misalignment of circadian and social time may be a risk factor for developing depression, especially in 31- to 40-yr-olds. These relationships should be further investigated in longitudinal studies to reveal if reduction of social jetlag should be part of prevention strategies. (Author correspondence: karla.allebrandt@med.uni-muenchen.de).

Links

Publisher Full Text

Authors+Show Affiliations

Levandovski R
Departamento de Psiquiatria e Medicina Legal, Universidade Federal do Rio Grande do Sul (UFRGS), Laboratório de Cronobiologia do Hospital de Clínicas de Porto Alegre (HCPA), Brazil.
Dantas G
No affiliation info available
Fernandes LC
No affiliation info available
Caumo W
No affiliation info available
Torres I
No affiliation info available
Roenneberg T
No affiliation info available
Hidalgo MP
No affiliation info available
Allebrandt KV
No affiliation info available

MeSH

AdolescentAdultAgedBrazilChronobiology DisordersChronotherapyCircadian RhythmDepressionFemaleHumansMaleMiddle AgedRisk FactorsRural PopulationSleepSocial BehaviorSurveys and QuestionnairesYoung Adult

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21895489

Citation

Levandovski, Rosa, et al. "Depression Scores Associate With Chronotype and Social Jetlag in a Rural Population." Chronobiology International, vol. 28, no. 9, 2011, pp. 771-8.
Levandovski R, Dantas G, Fernandes LC, et al. Depression scores associate with chronotype and social jetlag in a rural population. Chronobiol Int. 2011;28(9):771-8.
Levandovski, R., Dantas, G., Fernandes, L. C., Caumo, W., Torres, I., Roenneberg, T., Hidalgo, M. P., & Allebrandt, K. V. (2011). Depression scores associate with chronotype and social jetlag in a rural population. Chronobiology International, 28(9), 771-8. https://doi.org/10.3109/07420528.2011.602445
Levandovski R, et al. Depression Scores Associate With Chronotype and Social Jetlag in a Rural Population. Chronobiol Int. 2011;28(9):771-8. PubMed PMID: 21895489.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Depression scores associate with chronotype and social jetlag in a rural population. AU - Levandovski,Rosa, AU - Dantas,Giovana, AU - Fernandes,Luciana Carvalho, AU - Caumo,Wolnei, AU - Torres,Iraci, AU - Roenneberg,Till, AU - Hidalgo,Maria Paz Loayza, AU - Allebrandt,Karla Viviani, Y1 - 2011/09/06/ PY - 2011/9/8/entrez PY - 2011/9/8/pubmed PY - 2012/3/23/medline SP - 771 EP - 8 JF - Chronobiology international JO - Chronobiol Int VL - 28 IS - 9 N2 - In public health, mood disorders are among the most important mental impairments. Patients with depressive episodes exhibit daily mood variations, abnormal patterns in sleep-wake behavior, and in the daily rhythms of several endocrine-metabolic parameters. Although the relationship between the sleep/circadian processes and mood disorders is poorly understood, clock-related therapies, such as light therapy, sleep deprivation, and rigid sleep schedules, have been shown to be effective treatments. Several studies investigated the relationship between circadian phenotype (chronotype) and depression. These focused mainly on urban populations and assessed diurnal preferences (Morningness-Eveningness score) rather than the actual timing of sleep and activity. Here, we used the Beck Depression Inventory (BDI) in an essentially rural population (N?=?4051), and investigated its relation to circadian phenotype (chronotype and social jetlag), assessed with the Munich Chronotype Questionnaire (MCTQ). In our study design, we (i) normalized both chronotype and BDI scores for age and sex (MSF(sas) and BDI(as), respectively); (ii) calculated individual social jetlag (misalignment of the biological and social time); and (iii) investigated the relationship between circadian phenotypes and BDI scores in a population homogeneous in respect to culture, socioeconomic factors, and daily light exposure. A 15.65% (N?=?634) of the participants showed mild to severe depressive BDI scores. Late chronotypes had a higher BDI(as) than intermediate and early types, which was independent of whether or not the participants were smokers. Both chronotype and BDI(as) correlated positively with social jetlag. BDI(as) was significantly higher in subjects with >2?h of social jetlag than in the rest of the population?again independent of smoking status. We also compared chronotype and social jetlag distributions between BDI categories (no symptoms, minimal symptoms, and mild to severe symptoms of depression) separately for men and women and for four age groups; specifically in the age group 31?40 yrs, subjects with mild to severe BDI scores were significantly later chronotypes and suffered from higher social jetlag. Our results indicate that misalignment of circadian and social time may be a risk factor for developing depression, especially in 31- to 40-yr-olds. These relationships should be further investigated in longitudinal studies to reveal if reduction of social jetlag should be part of prevention strategies. (Author correspondence: karla.allebrandt@med.uni-muenchen.de). SN - 1525-6073 UR - https://www.unboundmedicine.com/medline/citation/21895489/Depression_scores_associate_with_chronotype_and_social_jetlag_in_a_rural_population_ L2 - https://www.tandfonline.com/doi/full/10.3109/07420528.2011.602445 DB - PRIME DP - Unbound Medicine ER -