TY - JOUR T1 - Molecularly imprinted microspheres as SPE sorbent for selective extraction of four Sudan dyes in catsup products. AU - Qiao,Fengxia, AU - Geng,Yuru, AU - He,Changqing, AU - Wu,Yupei, AU - Pan,Pengyu, Y1 - 2011/08/22/ PY - 2011/06/26/received PY - 2011/08/10/revised PY - 2011/08/10/accepted PY - 2011/9/9/entrez PY - 2011/9/9/pubmed PY - 2011/12/14/medline SP - 2891 EP - 6 JF - Journal of chromatography. B, Analytical technologies in the biomedical and life sciences JO - J Chromatogr B Analyt Technol Biomed Life Sci VL - 879 IS - 27 N2 - A highly selective molecularly imprinted solid-phase extraction (MISPE) coupled with high performance liquid chromatography (HPLC) ultraviolet-visible detection was developed for the simultaneous isolation and determination of four Sudan dyes (I, II, III and IV) in catsup products. The novel molecularly imprinted microspheres (MIM) were synthesized by aqueous suspension polymerization using phenylamine and naphthol as template, which showed high affinity to Sudan dyes in aqueous solution. In order to develop a selective extraction protocol for simultaneous determination the four Sudan dyes from catsup products, the molecular recognition properties of MIM as a SPE sorbent were evaluated. Under the optimized condition, good linearity was obtained from 0.01 to 2.5 μg g(-1) (r(2)≥ 0.9990) with the relative standard deviations of less than 3.4%. This proposed MISPE-HPLC procedure eliminated the effect of template leakage on quantitative analysis and could be applied to direct determination of four Sudan dyes in complicated food samples. SN - 1873-376X UR - https://www.unboundmedicine.com/medline/citation/21900053/Molecularly_imprinted_microspheres_as_SPE_sorbent_for_selective_extraction_of_four_Sudan_dyes_in_catsup_products_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1570-0232(11)00545-9 DB - PRIME DP - Unbound Medicine ER -