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A randomized controlled trial investigating the effects of a low-glycemic index diet on pregnancy outcomes in gestational diabetes mellitus.
Diabetes Care 2011; 34(11):2341-6DC

Abstract

OBJECTIVE

The prevalence of gestational diabetes mellitus (GDM) is rising. There is little evidence to demonstrate the effectiveness of one dietary therapy over another. We aimed to investigate the effect of a low-glycemic index (LGI) versus a conventional high-fiber diet on pregnancy outcomes, neonatal anthropometry, and maternal metabolic profile in GDM.

RESEARCH DESIGN AND METHODS

Ninety-nine women (age 26-42 years; mean ± SD prepregnancy BMI 24 ± 5 kg/m²) diagnosed with GDM at 20-32 weeks' gestation were randomized to follow either an LGI (n = 50; target glycemic index [GI] ~50) or a high-fiber moderate-GI diet (HF) (n = 49; target GI ~60). Dietary intake was assessed by 3-day food records. Pregnancy outcomes were collected from medical records.

RESULTS

The LGI group achieved a modestly lower GI than the HF group (mean ± SEM 47 ± 1 vs. 53 ± 1; P < 0.001). At birth, there was no significant difference in birth weight (LGI 3.3 ± 0.1 kg vs. HF 3.3 ± 0.1 kg; P = 0.619), birth weight centile (LGI 52.5 ± 4.3 vs. HF 52.2 ± 4.0; P = 0.969), prevalence of macrosomia (LGI 2.1% vs. HF 6.7%; P = 0.157), insulin treatment (LGI 53% vs. HF 65%; P = 0.251), or adverse pregnancy outcomes.

CONCLUSIONS

In intensively monitored women with GDM, an LGI diet and a conventional HF diet produce similar pregnancy outcomes.

Authors+Show Affiliations

School of Molecular Bioscience and Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, University of Sydney, Sydney, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21900148

Citation

Louie, Jimmy Chun Yu, et al. "A Randomized Controlled Trial Investigating the Effects of a Low-glycemic Index Diet On Pregnancy Outcomes in Gestational Diabetes Mellitus." Diabetes Care, vol. 34, no. 11, 2011, pp. 2341-6.
Louie JC, Markovic TP, Perera N, et al. A randomized controlled trial investigating the effects of a low-glycemic index diet on pregnancy outcomes in gestational diabetes mellitus. Diabetes Care. 2011;34(11):2341-6.
Louie, J. C., Markovic, T. P., Perera, N., Foote, D., Petocz, P., Ross, G. P., & Brand-Miller, J. C. (2011). A randomized controlled trial investigating the effects of a low-glycemic index diet on pregnancy outcomes in gestational diabetes mellitus. Diabetes Care, 34(11), pp. 2341-6. doi:10.2337/dc11-0985.
Louie JC, et al. A Randomized Controlled Trial Investigating the Effects of a Low-glycemic Index Diet On Pregnancy Outcomes in Gestational Diabetes Mellitus. Diabetes Care. 2011;34(11):2341-6. PubMed PMID: 21900148.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A randomized controlled trial investigating the effects of a low-glycemic index diet on pregnancy outcomes in gestational diabetes mellitus. AU - Louie,Jimmy Chun Yu, AU - Markovic,Tania P, AU - Perera,Nimalie, AU - Foote,Deborah, AU - Petocz,Peter, AU - Ross,Glynis P, AU - Brand-Miller,Jennie C, Y1 - 2011/09/06/ PY - 2011/9/9/entrez PY - 2011/9/9/pubmed PY - 2012/2/18/medline SP - 2341 EP - 6 JF - Diabetes care JO - Diabetes Care VL - 34 IS - 11 N2 - OBJECTIVE: The prevalence of gestational diabetes mellitus (GDM) is rising. There is little evidence to demonstrate the effectiveness of one dietary therapy over another. We aimed to investigate the effect of a low-glycemic index (LGI) versus a conventional high-fiber diet on pregnancy outcomes, neonatal anthropometry, and maternal metabolic profile in GDM. RESEARCH DESIGN AND METHODS: Ninety-nine women (age 26-42 years; mean ± SD prepregnancy BMI 24 ± 5 kg/m²) diagnosed with GDM at 20-32 weeks' gestation were randomized to follow either an LGI (n = 50; target glycemic index [GI] ~50) or a high-fiber moderate-GI diet (HF) (n = 49; target GI ~60). Dietary intake was assessed by 3-day food records. Pregnancy outcomes were collected from medical records. RESULTS: The LGI group achieved a modestly lower GI than the HF group (mean ± SEM 47 ± 1 vs. 53 ± 1; P < 0.001). At birth, there was no significant difference in birth weight (LGI 3.3 ± 0.1 kg vs. HF 3.3 ± 0.1 kg; P = 0.619), birth weight centile (LGI 52.5 ± 4.3 vs. HF 52.2 ± 4.0; P = 0.969), prevalence of macrosomia (LGI 2.1% vs. HF 6.7%; P = 0.157), insulin treatment (LGI 53% vs. HF 65%; P = 0.251), or adverse pregnancy outcomes. CONCLUSIONS: In intensively monitored women with GDM, an LGI diet and a conventional HF diet produce similar pregnancy outcomes. SN - 1935-5548 UR - https://www.unboundmedicine.com/medline/citation/21900148/A_randomized_controlled_trial_investigating_the_effects_of_a_low_glycemic_index_diet_on_pregnancy_outcomes_in_gestational_diabetes_mellitus_ L2 - http://care.diabetesjournals.org/cgi/pmidlookup?view=long&amp;pmid=21900148 DB - PRIME DP - Unbound Medicine ER -