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APTIMA® Trichomonas vaginalis, a transcription-mediated amplification assay for detection of Trichomonas vaginalis in urogenital specimens.
Expert Rev Mol Diagn. 2011 Sep; 11(7):679-88.ER

Abstract

The APTIMA(®) Trichomonas vaginalis (APTIMA TV; Gen-Probe Inc.) assay is the only amplification-based assay for T. vaginalis (TV) currently cleared by the US FDA. The assay was cleared in April 2011. APTIMA TV utilizes target capture specimen processing, transcription-mediated amplification and chemiluminescent probe hybridization for the qualitative detection of TV ribosomal RNA. The assay is used for the screening/diagnosis of trichomoniasis in women. Specimen types that can be used include physician-collected endocervical swabs, vaginal swabs, endocervical specimens collected in PreservCyt(®) (Thin Prep, Hologic Incorporated, MA, USA) solution and female urine specimens. The APTIMA TV assay has shown superior performance in side-by-side comparisons with other diagnostic methods in all patient populations and specimen types tested. Clinical sensitivity and specificity are >95 and 98%, respectively. The APTIMA TV assay fills a significant void in sexually transmitted infection diagnostics.

Authors+Show Affiliations

Department of Pathology, Rhode Island Hospital, Providence, RI, USA. kchapin@lifespan.orgNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

21902528

Citation

Chapin, Kimberle, and Sarah Andrea. "APTIMA® Trichomonas Vaginalis, a Transcription-mediated Amplification Assay for Detection of Trichomonas Vaginalis in Urogenital Specimens." Expert Review of Molecular Diagnostics, vol. 11, no. 7, 2011, pp. 679-88.
Chapin K, Andrea S. APTIMA® Trichomonas vaginalis, a transcription-mediated amplification assay for detection of Trichomonas vaginalis in urogenital specimens. Expert Rev Mol Diagn. 2011;11(7):679-88.
Chapin, K., & Andrea, S. (2011). APTIMA® Trichomonas vaginalis, a transcription-mediated amplification assay for detection of Trichomonas vaginalis in urogenital specimens. Expert Review of Molecular Diagnostics, 11(7), 679-88. https://doi.org/10.1586/erm.11.53
Chapin K, Andrea S. APTIMA® Trichomonas Vaginalis, a Transcription-mediated Amplification Assay for Detection of Trichomonas Vaginalis in Urogenital Specimens. Expert Rev Mol Diagn. 2011;11(7):679-88. PubMed PMID: 21902528.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - APTIMA® Trichomonas vaginalis, a transcription-mediated amplification assay for detection of Trichomonas vaginalis in urogenital specimens. AU - Chapin,Kimberle, AU - Andrea,Sarah, PY - 2011/9/10/entrez PY - 2011/9/10/pubmed PY - 2012/1/11/medline SP - 679 EP - 88 JF - Expert review of molecular diagnostics JO - Expert Rev Mol Diagn VL - 11 IS - 7 N2 - The APTIMA(®) Trichomonas vaginalis (APTIMA TV; Gen-Probe Inc.) assay is the only amplification-based assay for T. vaginalis (TV) currently cleared by the US FDA. The assay was cleared in April 2011. APTIMA TV utilizes target capture specimen processing, transcription-mediated amplification and chemiluminescent probe hybridization for the qualitative detection of TV ribosomal RNA. The assay is used for the screening/diagnosis of trichomoniasis in women. Specimen types that can be used include physician-collected endocervical swabs, vaginal swabs, endocervical specimens collected in PreservCyt(®) (Thin Prep, Hologic Incorporated, MA, USA) solution and female urine specimens. The APTIMA TV assay has shown superior performance in side-by-side comparisons with other diagnostic methods in all patient populations and specimen types tested. Clinical sensitivity and specificity are >95 and 98%, respectively. The APTIMA TV assay fills a significant void in sexually transmitted infection diagnostics. SN - 1744-8352 UR - https://www.unboundmedicine.com/medline/citation/21902528/APTIMA®_Trichomonas_vaginalis_a_transcription_mediated_amplification_assay_for_detection_of_Trichomonas_vaginalis_in_urogenital_specimens_ DB - PRIME DP - Unbound Medicine ER -