TY - JOUR T1 - APTIMA® Trichomonas vaginalis, a transcription-mediated amplification assay for detection of Trichomonas vaginalis in urogenital specimens. AU - Chapin,Kimberle, AU - Andrea,Sarah, PY - 2011/9/10/entrez PY - 2011/9/10/pubmed PY - 2012/1/11/medline SP - 679 EP - 88 JF - Expert review of molecular diagnostics JO - Expert Rev Mol Diagn VL - 11 IS - 7 N2 - The APTIMA(®) Trichomonas vaginalis (APTIMA TV; Gen-Probe Inc.) assay is the only amplification-based assay for T. vaginalis (TV) currently cleared by the US FDA. The assay was cleared in April 2011. APTIMA TV utilizes target capture specimen processing, transcription-mediated amplification and chemiluminescent probe hybridization for the qualitative detection of TV ribosomal RNA. The assay is used for the screening/diagnosis of trichomoniasis in women. Specimen types that can be used include physician-collected endocervical swabs, vaginal swabs, endocervical specimens collected in PreservCyt(®) (Thin Prep, Hologic Incorporated, MA, USA) solution and female urine specimens. The APTIMA TV assay has shown superior performance in side-by-side comparisons with other diagnostic methods in all patient populations and specimen types tested. Clinical sensitivity and specificity are >95 and 98%, respectively. The APTIMA TV assay fills a significant void in sexually transmitted infection diagnostics. SN - 1744-8352 UR - https://www.unboundmedicine.com/medline/citation/21902528/APTIMA��_Trichomonas_vaginalis_a_transcription_mediated_amplification_assay_for_detection_of_Trichomonas_vaginalis_in_urogenital_specimens_ DB - PRIME DP - Unbound Medicine ER -