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Electrochemically selective determination of dopamine in the presence of ascorbic and uric acids on the surface of the modified Nafion/single wall carbon nanotube/poly(3-methylthiophene) glassy carbon electrodes.
Colloids Surf B Biointerfaces. 2011 Dec 01; 88(2):764-70.CS

Abstract

A voltammetric method based on a combination of incorporated Nafion, single-walled carbon nanotubes and poly(3-methylthiophene) film-modified glassy carbon electrode (NF/SWCNT/PMT/GCE) has been successfully developed for selective determination of dopamine (DA) in the ternary mixture of dopamine, ascorbic acid (AA) and uric acid (UA) in 0.1M phosphate buffer solution (PBS) pH 4. It was shown that to detect DA from binary DA-AA mixture, the use of NF/PMT/GCE was sufficient, but to detect DA from ternary DA-AA-UA mixture NF/SWCNT/PMT/GCE was required. The later modified electrode exhibits superior electrocatalytic activity towards AA, DA and UA thanks to synergic effect of NF/SWCNT (combining unique properties of SWCNT such as high specific surface area, electrocatalytic and adsorptive properties, with the cation selectivity of NF). On the surface of NF/SWCNT/PMT/GCE AA, DA, UA were oxidized respectively at distinguishable potentials of 0.15, 0.37 and 0.53 V (vs. Ag/AgCl), to form well-defined and sharp peaks, making possible simultaneous determination of each compound. Also, it has several advantages, such as simple preparation method, high sensitivity, low detection limit and excellent reproducibility. Thus, the proposed NF/SWCNT/PMT/GCE could be advantageously employed for the determination of DA in real pharmaceutical formulations.

Authors+Show Affiliations

Research Centre for Environmental Technology and Sustainable Development, Hanoi University of Science, 334 Nguyen Trai Road, Ha Noi, Viet Nam. doquan@vnu.edu.vnNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21907551

Citation

Quan, Do Phuc, et al. "Electrochemically Selective Determination of Dopamine in the Presence of Ascorbic and Uric Acids On the Surface of the Modified Nafion/single Wall Carbon Nanotube/poly(3-methylthiophene) Glassy Carbon Electrodes." Colloids and Surfaces. B, Biointerfaces, vol. 88, no. 2, 2011, pp. 764-70.
Quan do P, Tuyen do P, Lam TD, et al. Electrochemically selective determination of dopamine in the presence of ascorbic and uric acids on the surface of the modified Nafion/single wall carbon nanotube/poly(3-methylthiophene) glassy carbon electrodes. Colloids Surf B Biointerfaces. 2011;88(2):764-70.
Quan, d. o. . P., Tuyen, d. o. . P., Lam, T. D., Tram, P. T., Binh, N. H., & Viet, P. H. (2011). Electrochemically selective determination of dopamine in the presence of ascorbic and uric acids on the surface of the modified Nafion/single wall carbon nanotube/poly(3-methylthiophene) glassy carbon electrodes. Colloids and Surfaces. B, Biointerfaces, 88(2), 764-70. https://doi.org/10.1016/j.colsurfb.2011.08.012
Quan do P, et al. Electrochemically Selective Determination of Dopamine in the Presence of Ascorbic and Uric Acids On the Surface of the Modified Nafion/single Wall Carbon Nanotube/poly(3-methylthiophene) Glassy Carbon Electrodes. Colloids Surf B Biointerfaces. 2011 Dec 1;88(2):764-70. PubMed PMID: 21907551.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Electrochemically selective determination of dopamine in the presence of ascorbic and uric acids on the surface of the modified Nafion/single wall carbon nanotube/poly(3-methylthiophene) glassy carbon electrodes. AU - Quan,Do Phuc, AU - Tuyen,Do Phuc, AU - Lam,Tran Dai, AU - Tram,Phan Thi Ngoc, AU - Binh,Nguyen Hai, AU - Viet,Pham Hung, Y1 - 2011/08/22/ PY - 2011/05/13/received PY - 2011/08/11/revised PY - 2011/08/12/accepted PY - 2011/9/13/entrez PY - 2011/9/13/pubmed PY - 2012/2/7/medline SP - 764 EP - 70 JF - Colloids and surfaces. B, Biointerfaces JO - Colloids Surf B Biointerfaces VL - 88 IS - 2 N2 - A voltammetric method based on a combination of incorporated Nafion, single-walled carbon nanotubes and poly(3-methylthiophene) film-modified glassy carbon electrode (NF/SWCNT/PMT/GCE) has been successfully developed for selective determination of dopamine (DA) in the ternary mixture of dopamine, ascorbic acid (AA) and uric acid (UA) in 0.1M phosphate buffer solution (PBS) pH 4. It was shown that to detect DA from binary DA-AA mixture, the use of NF/PMT/GCE was sufficient, but to detect DA from ternary DA-AA-UA mixture NF/SWCNT/PMT/GCE was required. The later modified electrode exhibits superior electrocatalytic activity towards AA, DA and UA thanks to synergic effect of NF/SWCNT (combining unique properties of SWCNT such as high specific surface area, electrocatalytic and adsorptive properties, with the cation selectivity of NF). On the surface of NF/SWCNT/PMT/GCE AA, DA, UA were oxidized respectively at distinguishable potentials of 0.15, 0.37 and 0.53 V (vs. Ag/AgCl), to form well-defined and sharp peaks, making possible simultaneous determination of each compound. Also, it has several advantages, such as simple preparation method, high sensitivity, low detection limit and excellent reproducibility. Thus, the proposed NF/SWCNT/PMT/GCE could be advantageously employed for the determination of DA in real pharmaceutical formulations. SN - 1873-4367 UR - https://www.unboundmedicine.com/medline/citation/21907551/Electrochemically_selective_determination_of_dopamine_in_the_presence_of_ascorbic_and_uric_acids_on_the_surface_of_the_modified_Nafion/single_wall_carbon_nanotube/poly_3_methylthiophene__glassy_carbon_electrodes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0927-7765(11)00490-5 DB - PRIME DP - Unbound Medicine ER -