Tags

Type your tag names separated by a space and hit enter

Prevalence and characteristics of primary angle-closure diseases in a rural adult Chinese population: the Handan Eye Study.
Invest Ophthalmol Vis Sci 2011; 52(12):8672-9IO

Abstract

PURPOSE

To investigate the prevalence and characteristics of primary angle-closure suspect (PACS), primary angle closure (PAC), and primary angle-closure glaucoma (PACG) in a rural population in China.

METHODS

In all, 6716 Han Chinese 30 years of age and older (5480 subjects 40 years of age and older) from 13 villages in Handan were randomly selected and completed an ophthalmologic examination, including visual acuity, intraocular pressure (IOP), slit-lamp examination, gonioscopy and stereoscopic photography, and visual field. PACS was defined as present if either eye had the posterior trabecular meshwork not visible for 180° or more on gonioscopy. PAC was present in an eye with PACS and peripheral anterior synechiae (PAS) and/or IOP ≥ 21 mm Hg, but without glaucomatous neuropathy (GON). PACG was defined as PAC with evidence of GON.

RESULTS

The standardized prevalences of PACG, PAC, and PACS were 0.5% (95% confidence interval [CI]: 0.3-0.7%), 1.5% (95% CI: 1.2-1.8%), and 10.4% (95% CI: 9.6-11.2%) in those 40 years of age and older. The prevalence of all three conditions increased with age (P < 0.001). Females had much higher rates of PACS, PAC, and PACG (P < 0.05); 21 persons with PACG (65%) were blind in at least one eye: 13 were due to glaucoma and the other 8 likely had other causes.

CONCLUSIONS

The prevalence of PACS, PAC, and PACG in this rural population is similar to what was previously reported in urban Chinese residents. Two thirds of those with PACG were blind in at least one eye. Strategies to detect and treat this preventable disease in rural China are needed.

Authors+Show Affiliations

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21908580

Citation

Liang, Yuanbo, et al. "Prevalence and Characteristics of Primary Angle-closure Diseases in a Rural Adult Chinese Population: the Handan Eye Study." Investigative Ophthalmology & Visual Science, vol. 52, no. 12, 2011, pp. 8672-9.
Liang Y, Friedman DS, Zhou Q, et al. Prevalence and characteristics of primary angle-closure diseases in a rural adult Chinese population: the Handan Eye Study. Invest Ophthalmol Vis Sci. 2011;52(12):8672-9.
Liang, Y., Friedman, D. S., Zhou, Q., Yang, X. H., Sun, L. P., Guo, L., ... Wang, N. L. (2011). Prevalence and characteristics of primary angle-closure diseases in a rural adult Chinese population: the Handan Eye Study. Investigative Ophthalmology & Visual Science, 52(12), pp. 8672-9. doi:10.1167/iovs.11-7480.
Liang Y, et al. Prevalence and Characteristics of Primary Angle-closure Diseases in a Rural Adult Chinese Population: the Handan Eye Study. Invest Ophthalmol Vis Sci. 2011 Nov 7;52(12):8672-9. PubMed PMID: 21908580.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and characteristics of primary angle-closure diseases in a rural adult Chinese population: the Handan Eye Study. AU - Liang,Yuanbo, AU - Friedman,David S, AU - Zhou,Qiang, AU - Yang,Xiao Hui, AU - Sun,Lan Ping, AU - Guo,Lixia, AU - Chang,Dolly S, AU - Lian,Liying, AU - Wang,Ning Li, AU - ,, Y1 - 2011/11/07/ PY - 2011/9/13/entrez PY - 2011/9/13/pubmed PY - 2012/1/6/medline SP - 8672 EP - 9 JF - Investigative ophthalmology & visual science JO - Invest. Ophthalmol. Vis. Sci. VL - 52 IS - 12 N2 - PURPOSE: To investigate the prevalence and characteristics of primary angle-closure suspect (PACS), primary angle closure (PAC), and primary angle-closure glaucoma (PACG) in a rural population in China. METHODS: In all, 6716 Han Chinese 30 years of age and older (5480 subjects 40 years of age and older) from 13 villages in Handan were randomly selected and completed an ophthalmologic examination, including visual acuity, intraocular pressure (IOP), slit-lamp examination, gonioscopy and stereoscopic photography, and visual field. PACS was defined as present if either eye had the posterior trabecular meshwork not visible for 180° or more on gonioscopy. PAC was present in an eye with PACS and peripheral anterior synechiae (PAS) and/or IOP ≥ 21 mm Hg, but without glaucomatous neuropathy (GON). PACG was defined as PAC with evidence of GON. RESULTS: The standardized prevalences of PACG, PAC, and PACS were 0.5% (95% confidence interval [CI]: 0.3-0.7%), 1.5% (95% CI: 1.2-1.8%), and 10.4% (95% CI: 9.6-11.2%) in those 40 years of age and older. The prevalence of all three conditions increased with age (P < 0.001). Females had much higher rates of PACS, PAC, and PACG (P < 0.05); 21 persons with PACG (65%) were blind in at least one eye: 13 were due to glaucoma and the other 8 likely had other causes. CONCLUSIONS: The prevalence of PACS, PAC, and PACG in this rural population is similar to what was previously reported in urban Chinese residents. Two thirds of those with PACG were blind in at least one eye. Strategies to detect and treat this preventable disease in rural China are needed. SN - 1552-5783 UR - https://www.unboundmedicine.com/medline/citation/21908580/Prevalence_and_characteristics_of_primary_angle_closure_diseases_in_a_rural_adult_Chinese_population:_the_Handan_Eye_Study_ L2 - http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.11-7480 DB - PRIME DP - Unbound Medicine ER -