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Antifungal activity of Ocimum sanctum Linn. (Lamiaceae) on clinically isolated dermatophytic fungi.
Asian Pac J Trop Med. 2011 Aug; 4(8):654-7.AP

Abstract

OBJECTIVE

To assess antifungal activity of Ocimum sanctum leaves against dermatophytic fungi.

METHODS

Antifungal activity of Ocimum sanctum leaves was measured by 38 A NCCLS method. Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of various extracts and fractions of Ocimum sanctum leaves were also determined.

RESULTS

Ocimum sanctum leaves possessed antifungal activity against clinically isolated dermatophytes at the concentration of 200 μg/mL. MIC and MFC were high with water fraction (200 μg/mL) against dermatophytic fungi used.

CONCLUSIONS

Ocimum sanctum has antifungal activity, and the leaf extracts may be a useful source for dermatophytic infections.

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Authors+Show Affiliations

Balakumar S
Department of Chemistry and Biosciences, SASTRA University, Srinivasa Ramanujan Centre, Kumbakonam, Tamil Nadu, India.
Rajan S
No affiliation info available
Thirunalasundari T
No affiliation info available
Jeeva S
No affiliation info available

MeSH

Antifungal AgentsEpidermophytonHumansMiconazoleMicrobial Sensitivity TestsOcimumPlant ExtractsPlant LeavesSolventsTineaWater

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21914546

Citation

Balakumar, S, et al. "Antifungal Activity of Ocimum Sanctum Linn. (Lamiaceae) On Clinically Isolated Dermatophytic Fungi." Asian Pacific Journal of Tropical Medicine, vol. 4, no. 8, 2011, pp. 654-7.
Balakumar S, Rajan S, Thirunalasundari T, et al. Antifungal activity of Ocimum sanctum Linn. (Lamiaceae) on clinically isolated dermatophytic fungi. Asian Pac J Trop Med. 2011;4(8):654-7.
Balakumar, S., Rajan, S., Thirunalasundari, T., & Jeeva, S. (2011). Antifungal activity of Ocimum sanctum Linn. (Lamiaceae) on clinically isolated dermatophytic fungi. Asian Pacific Journal of Tropical Medicine, 4(8), 654-7. https://doi.org/10.1016/S1995-7645(11)60166-1
Balakumar S, et al. Antifungal Activity of Ocimum Sanctum Linn. (Lamiaceae) On Clinically Isolated Dermatophytic Fungi. Asian Pac J Trop Med. 2011;4(8):654-7. PubMed PMID: 21914546.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antifungal activity of Ocimum sanctum Linn. (Lamiaceae) on clinically isolated dermatophytic fungi. AU - Balakumar,S, AU - Rajan,S, AU - Thirunalasundari,T, AU - Jeeva,S, PY - 2011/02/21/received PY - 2011/04/20/revised PY - 2011/07/15/accepted PY - 2011/9/15/entrez PY - 2011/9/15/pubmed PY - 2012/1/28/medline SP - 654 EP - 7 JF - Asian Pacific journal of tropical medicine JO - Asian Pac J Trop Med VL - 4 IS - 8 N2 - OBJECTIVE: To assess antifungal activity of Ocimum sanctum leaves against dermatophytic fungi. METHODS: Antifungal activity of Ocimum sanctum leaves was measured by 38 A NCCLS method. Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of various extracts and fractions of Ocimum sanctum leaves were also determined. RESULTS: Ocimum sanctum leaves possessed antifungal activity against clinically isolated dermatophytes at the concentration of 200 μg/mL. MIC and MFC were high with water fraction (200 μg/mL) against dermatophytic fungi used. CONCLUSIONS: Ocimum sanctum has antifungal activity, and the leaf extracts may be a useful source for dermatophytic infections. SN - 2352-4146 UR - https://www.unboundmedicine.com/medline/citation/21914546/Antifungal_activity_of_Ocimum_sanctum_Linn___Lamiaceae__on_clinically_isolated_dermatophytic_fungi_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1995-7645(11)60166-1 DB - PRIME DP - Unbound Medicine ER -