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Characterization of polyethylenimine by electrospray ionization and matrix-assisted laser desorption/ionization.
J Mass Spectrom. 2011 Sep; 46(9):876-83.JM

Abstract

Branched polyethylenimines (PEIs) with lower average molecular weights (600, 1200 and 1800 Da) have been studied by Electrospray Ionization (ESI) and Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry. In both, ESI and MALDI mass spectra, the main distribution arises from protonated PEI oligomers with NH(2) end groups, [PEI + H](+), which are observed at m/z 43n + 18. A trace of sodium contamination in the PEI samples results in the presence of a series that appears at m/z 43n + 40 [PEI + Na](+). However, only the MALDI mass spectra show a [PEI + K](+) series at m/z 43n + 56, because of matrix contamination with potassium, and a series generated by condensation of the matrix with PEI at m/z 43n + 30. Collisionally activated dissociation tandem mass spectrometry (CAD (MS/MS)) of protonated PEI oligomers is shown to yield three fragment ion series b(n), cn″ and K(n). The experiments have demonstrated the capabilities of these mass spectrometry techniques, along with CAD MS/MS to detect and characterize such polar synthetic polymers.

Authors+Show Affiliations

Department of Chemistry, The University of Akron, Akron, Ohio, USA. edgardo.rivera14@upr.eduNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21915951

Citation

Rivera-Tirado, Edgardo, and Chrys Wesdemiotis. "Characterization of Polyethylenimine By Electrospray Ionization and Matrix-assisted Laser Desorption/ionization." Journal of Mass Spectrometry : JMS, vol. 46, no. 9, 2011, pp. 876-83.
Rivera-Tirado E, Wesdemiotis C. Characterization of polyethylenimine by electrospray ionization and matrix-assisted laser desorption/ionization. J Mass Spectrom. 2011;46(9):876-83.
Rivera-Tirado, E., & Wesdemiotis, C. (2011). Characterization of polyethylenimine by electrospray ionization and matrix-assisted laser desorption/ionization. Journal of Mass Spectrometry : JMS, 46(9), 876-83. https://doi.org/10.1002/jms.1964
Rivera-Tirado E, Wesdemiotis C. Characterization of Polyethylenimine By Electrospray Ionization and Matrix-assisted Laser Desorption/ionization. J Mass Spectrom. 2011;46(9):876-83. PubMed PMID: 21915951.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Characterization of polyethylenimine by electrospray ionization and matrix-assisted laser desorption/ionization. AU - Rivera-Tirado,Edgardo, AU - Wesdemiotis,Chrys, PY - 2011/9/15/entrez PY - 2011/9/15/pubmed PY - 2011/12/13/medline SP - 876 EP - 83 JF - Journal of mass spectrometry : JMS JO - J Mass Spectrom VL - 46 IS - 9 N2 - Branched polyethylenimines (PEIs) with lower average molecular weights (600, 1200 and 1800 Da) have been studied by Electrospray Ionization (ESI) and Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry. In both, ESI and MALDI mass spectra, the main distribution arises from protonated PEI oligomers with NH(2) end groups, [PEI + H](+), which are observed at m/z 43n + 18. A trace of sodium contamination in the PEI samples results in the presence of a series that appears at m/z 43n + 40 [PEI + Na](+). However, only the MALDI mass spectra show a [PEI + K](+) series at m/z 43n + 56, because of matrix contamination with potassium, and a series generated by condensation of the matrix with PEI at m/z 43n + 30. Collisionally activated dissociation tandem mass spectrometry (CAD (MS/MS)) of protonated PEI oligomers is shown to yield three fragment ion series b(n), cn″ and K(n). The experiments have demonstrated the capabilities of these mass spectrometry techniques, along with CAD MS/MS to detect and characterize such polar synthetic polymers. SN - 1096-9888 UR - https://www.unboundmedicine.com/medline/citation/21915951/Characterization_of_polyethylenimine_by_electrospray_ionization_and_matrix_assisted_laser_desorption/ionization_ DB - PRIME DP - Unbound Medicine ER -