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Convenient synthesis of 3-vinyl and 3-styryl coumarins.
Org Lett. 2011 Oct 07; 13(19):5112-5.OL

Abstract

A variety of 2-hydroxy aldehydes on reaction with 3-butenoic acid afford in a one-pot reaction the corresponding 3-vinylcoumarins. As expected, extension of the delocalized π-electron system accomplished by Heck coupling reactions with aryl halides results in an increased fluorescence of the compounds whose applicability is yet to be established.

Authors+Show Affiliations

REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, FCT, Universidade Nova de Lisboa, Portugal.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21916521

Citation

Gordo, Joana, et al. "Convenient Synthesis of 3-vinyl and 3-styryl Coumarins." Organic Letters, vol. 13, no. 19, 2011, pp. 5112-5.
Gordo J, Avó J, Parola AJ, et al. Convenient synthesis of 3-vinyl and 3-styryl coumarins. Org Lett. 2011;13(19):5112-5.
Gordo, J., Avó, J., Parola, A. J., Lima, J. C., Pereira, A., & Branco, P. S. (2011). Convenient synthesis of 3-vinyl and 3-styryl coumarins. Organic Letters, 13(19), 5112-5. https://doi.org/10.1021/ol201983u
Gordo J, et al. Convenient Synthesis of 3-vinyl and 3-styryl Coumarins. Org Lett. 2011 Oct 7;13(19):5112-5. PubMed PMID: 21916521.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Convenient synthesis of 3-vinyl and 3-styryl coumarins. AU - Gordo,Joana, AU - Avó,João, AU - Parola,A Jorge, AU - Lima,João C, AU - Pereira,António, AU - Branco,Paula S, Y1 - 2011/09/15/ PY - 2011/9/16/entrez PY - 2011/9/16/pubmed PY - 2012/1/18/medline SP - 5112 EP - 5 JF - Organic letters JO - Org Lett VL - 13 IS - 19 N2 - A variety of 2-hydroxy aldehydes on reaction with 3-butenoic acid afford in a one-pot reaction the corresponding 3-vinylcoumarins. As expected, extension of the delocalized π-electron system accomplished by Heck coupling reactions with aryl halides results in an increased fluorescence of the compounds whose applicability is yet to be established. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/21916521/Convenient_synthesis_of_3_vinyl_and_3_styryl_coumarins_ L2 - https://doi.org/10.1021/ol201983u DB - PRIME DP - Unbound Medicine ER -