Tags

Type your tag names separated by a space and hit enter

Subtypes of irritable bowel syndrome on Rome III criteria: a multicenter study.
J Gastroenterol Hepatol. 2012 Apr; 27(4):760-5.JG

Abstract

BACKGROUND AND AIM

The aim of this study was to explore the distribution and clinical characteristics of four subtypes of irritable bowel syndrome (IBS) based on Rome III criteria in Chinese.

METHODS

A total of 754 consecutive IBS outpatients from three tertiary hospitals in China were included. Diagnostic criteria were based on Rome II or Rome III.

RESULTS

Among 754 outpatients, 510 (67.6%) patients met the Rome II criteria, 735 (97.5%) patients met the Rome III criteria and 492 (65.3%) patients met both sets of criteria. Among 735 patients who met the Rome III criteria, 66.3% had IBS with diarrhea (IBS-D), 14.7% had IBS with constipation (IBS-C), 4.2% had mixed IBS (IBS-M) and 14.8% had unsubtyped IBS (IBS-U). Most of the IBS-D, IBS-C and IBS-M patients based on the Rome III criteria matched the diarrhea-predominant IBS, constipation-predominant IBS and alternating IBS based on the Rome II criteria, respectively. Among IBS-U patients, 57.0%, 33.3% and 9.7% had constipation-predominant IBS, diarrhea-predominant IBS and alternating IBS, respectively. For IBS-M, the frequencies of bowel movements were stable in 48.4% patients and variable in 51.6% patients. Defecation urgency and straining were most frequent in IBS-M and least frequent in IBS-U patients than other subtypes. About 77.2% of IBS-U patients had abnormal stool frequency (< 3 times/week or > 3 times/day).

CONCLUSION

The Rome III criteria are more sensitive and practical in diagnosing IBS. IBS-D is the most frequent subtype, which is followed by IBS-U, IBS-C and IBS-M. IBS-U is a new subtype, which warrants further studies.

Authors+Show Affiliations

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

21929652

Citation

Yao, Xin, et al. "Subtypes of Irritable Bowel Syndrome On Rome III Criteria: a Multicenter Study." Journal of Gastroenterology and Hepatology, vol. 27, no. 4, 2012, pp. 760-5.
Yao X, Yang YS, Cui LH, et al. Subtypes of irritable bowel syndrome on Rome III criteria: a multicenter study. J Gastroenterol Hepatol. 2012;27(4):760-5.
Yao, X., Yang, Y. S., Cui, L. H., Zhao, K. B., Zhang, Z. H., Peng, L. H., Guo, X., Sun, G., Shang, J., Wang, W. F., Feng, J., & Huang, Q. (2012). Subtypes of irritable bowel syndrome on Rome III criteria: a multicenter study. Journal of Gastroenterology and Hepatology, 27(4), 760-5. https://doi.org/10.1111/j.1440-1746.2011.06930.x
Yao X, et al. Subtypes of Irritable Bowel Syndrome On Rome III Criteria: a Multicenter Study. J Gastroenterol Hepatol. 2012;27(4):760-5. PubMed PMID: 21929652.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Subtypes of irritable bowel syndrome on Rome III criteria: a multicenter study. AU - Yao,Xin, AU - Yang,Yun Sheng, AU - Cui,Li Hong, AU - Zhao,Ka Bing, AU - Zhang,Zhen Hua, AU - Peng,Li Hua, AU - Guo,Xu, AU - Sun,Gang, AU - Shang,Jun, AU - Wang,Wei Feng, AU - Feng,Jia, AU - Huang,Qiyang, PY - 2011/9/21/entrez PY - 2011/9/21/pubmed PY - 2012/8/7/medline SP - 760 EP - 5 JF - Journal of gastroenterology and hepatology JO - J. Gastroenterol. Hepatol. VL - 27 IS - 4 N2 - BACKGROUND AND AIM: The aim of this study was to explore the distribution and clinical characteristics of four subtypes of irritable bowel syndrome (IBS) based on Rome III criteria in Chinese. METHODS: A total of 754 consecutive IBS outpatients from three tertiary hospitals in China were included. Diagnostic criteria were based on Rome II or Rome III. RESULTS: Among 754 outpatients, 510 (67.6%) patients met the Rome II criteria, 735 (97.5%) patients met the Rome III criteria and 492 (65.3%) patients met both sets of criteria. Among 735 patients who met the Rome III criteria, 66.3% had IBS with diarrhea (IBS-D), 14.7% had IBS with constipation (IBS-C), 4.2% had mixed IBS (IBS-M) and 14.8% had unsubtyped IBS (IBS-U). Most of the IBS-D, IBS-C and IBS-M patients based on the Rome III criteria matched the diarrhea-predominant IBS, constipation-predominant IBS and alternating IBS based on the Rome II criteria, respectively. Among IBS-U patients, 57.0%, 33.3% and 9.7% had constipation-predominant IBS, diarrhea-predominant IBS and alternating IBS, respectively. For IBS-M, the frequencies of bowel movements were stable in 48.4% patients and variable in 51.6% patients. Defecation urgency and straining were most frequent in IBS-M and least frequent in IBS-U patients than other subtypes. About 77.2% of IBS-U patients had abnormal stool frequency (< 3 times/week or > 3 times/day). CONCLUSION: The Rome III criteria are more sensitive and practical in diagnosing IBS. IBS-D is the most frequent subtype, which is followed by IBS-U, IBS-C and IBS-M. IBS-U is a new subtype, which warrants further studies. SN - 1440-1746 UR - https://www.unboundmedicine.com/medline/citation/21929652/Subtypes_of_irritable_bowel_syndrome_on_Rome_III_criteria:_a_multicenter_study_ L2 - https://doi.org/10.1111/j.1440-1746.2011.06930.x DB - PRIME DP - Unbound Medicine ER -