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Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work?
Eur Heart J 2012; 33(4):436-43EH

Abstract

Omega-3 fatty acids, which are found abundantly in fish oil, exert pleiotropic cardiometabolic effects with a diverse range of actions. The results of previous studies raised a lot of interest in the role of fish oil and omega-3 fatty acids in primary and secondary prevention of cardiovascular diseases. The present review will focus on the current clinical uses of omega-3 fatty acids and provide an update on their effects. Since recently published trials in patients with coronary artery diseases or post-myocardial infarction did not show an effect of omega-3 fatty acids on major cardiovascular endpoints, this review will examine the limitations of those data and suggest recommendations for the use of omega-3 fatty acids.

Authors+Show Affiliations

Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands. daan.kromhout@wur.nlNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

21933782

Citation

Kromhout, Daan, et al. "Fish Oil and Omega-3 Fatty Acids in Cardiovascular Disease: Do They Really Work?" European Heart Journal, vol. 33, no. 4, 2012, pp. 436-43.
Kromhout D, Yasuda S, Geleijnse JM, et al. Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work? Eur Heart J. 2012;33(4):436-43.
Kromhout, D., Yasuda, S., Geleijnse, J. M., & Shimokawa, H. (2012). Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work? European Heart Journal, 33(4), pp. 436-43. doi:10.1093/eurheartj/ehr362.
Kromhout D, et al. Fish Oil and Omega-3 Fatty Acids in Cardiovascular Disease: Do They Really Work. Eur Heart J. 2012;33(4):436-43. PubMed PMID: 21933782.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work? AU - Kromhout,Daan, AU - Yasuda,Satoshi, AU - Geleijnse,Johanna M, AU - Shimokawa,Hiroaki, Y1 - 2011/09/19/ PY - 2011/9/22/entrez PY - 2011/9/22/pubmed PY - 2012/4/17/medline SP - 436 EP - 43 JF - European heart journal JO - Eur. Heart J. VL - 33 IS - 4 N2 - Omega-3 fatty acids, which are found abundantly in fish oil, exert pleiotropic cardiometabolic effects with a diverse range of actions. The results of previous studies raised a lot of interest in the role of fish oil and omega-3 fatty acids in primary and secondary prevention of cardiovascular diseases. The present review will focus on the current clinical uses of omega-3 fatty acids and provide an update on their effects. Since recently published trials in patients with coronary artery diseases or post-myocardial infarction did not show an effect of omega-3 fatty acids on major cardiovascular endpoints, this review will examine the limitations of those data and suggest recommendations for the use of omega-3 fatty acids. SN - 1522-9645 UR - https://www.unboundmedicine.com/medline/citation/21933782/Fish_oil_and_omega_3_fatty_acids_in_cardiovascular_disease:_do_they_really_work L2 - https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehr362 DB - PRIME DP - Unbound Medicine ER -