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Female breast, lung, and pelvic organ radiation from dose-reduced 64-MDCT thoracic examination protocols: a phantom study.
AJR Am J Roentgenol. 2011 Oct; 197(4):929-34.AA

Abstract

OBJECTIVE

We compared phantom organ doses delivered to breast, lung, and pelvis by five protocols using current dose reduction methods for routine chest CT and pulmonary CT angiography.

MATERIALS AND METHODS

We measured the radiation dose to an anthropomorphic phantom using 64-MDCT with metal oxide semiconductor field effect transistor (MOSFET) detectors in the breast (skin and parenchyma), the lungs, and the pelvis (upper and lower). We compared the following five protocols: protocol 1, 120 kVp, automatic dose modulation, 120-320 mA; protocol 2, 120 kVp, automatic dose modulation, 60-200 mA; protocol 3, 100 kVp and fixed dose of 200 mA; protocol 4, 120 kVp, automatic dose modulation, 200-394 mA; and protocol 5, 80 kVp and fixed dose of 120 mA. Organ doses in milligrays and as a percentage of the volume CT dose index (CTDI(vol)) were compared using the analysis of variance for repeated measurements.

RESULTS

Protocol 1 delivered the highest breast dose (mean ± SD, 15.8 ± 1.8 mGy; 110.5% of CTDI(vol)). A decrease in breast radiation of more than 50% was achieved with protocol 3 (4.8 ± 1.8 mGy; 91.7% of CTDI(vol)) compared with protocol 4 (13.1 ± 5.5 mGy; 87.0% of CTDI(vol)) (p = 0.003). The lung received the highest organ dose regardless of the protocol (protocol 4: 21.5 ± 1.7 mGy; 142.5% of CTDI(vol)). Pelvic radiation was low regardless of protocol and did not exceed 0.2 mGy (up to 3.7% of CTDI(vol); p = 0.118-0.999).

CONCLUSION

The results of this anthropomorphic phantom study showed substantial and significant variation in radiation doses to the breast and lungs depending on the scanning protocol used with the potential for over threefold dose reduction.

Authors+Show Affiliations

Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA. dlitmano@bidmc.harvard.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

21940581

Citation

Litmanovich, Diana, et al. "Female Breast, Lung, and Pelvic Organ Radiation From Dose-reduced 64-MDCT Thoracic Examination Protocols: a Phantom Study." AJR. American Journal of Roentgenology, vol. 197, no. 4, 2011, pp. 929-34.
Litmanovich D, Tack D, Lin PJ, et al. Female breast, lung, and pelvic organ radiation from dose-reduced 64-MDCT thoracic examination protocols: a phantom study. AJR Am J Roentgenol. 2011;197(4):929-34.
Litmanovich, D., Tack, D., Lin, P. J., Boiselle, P. M., Raptopoulos, V., & Bankier, A. A. (2011). Female breast, lung, and pelvic organ radiation from dose-reduced 64-MDCT thoracic examination protocols: a phantom study. AJR. American Journal of Roentgenology, 197(4), 929-34. https://doi.org/10.2214/AJR.10.6401
Litmanovich D, et al. Female Breast, Lung, and Pelvic Organ Radiation From Dose-reduced 64-MDCT Thoracic Examination Protocols: a Phantom Study. AJR Am J Roentgenol. 2011;197(4):929-34. PubMed PMID: 21940581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Female breast, lung, and pelvic organ radiation from dose-reduced 64-MDCT thoracic examination protocols: a phantom study. AU - Litmanovich,Diana, AU - Tack,Denis, AU - Lin,Pei-Jan P, AU - Boiselle,Phillip M, AU - Raptopoulos,Vassilios, AU - Bankier,Alexander A, PY - 2011/9/24/entrez PY - 2011/9/24/pubmed PY - 2011/12/13/medline SP - 929 EP - 34 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 197 IS - 4 N2 - OBJECTIVE: We compared phantom organ doses delivered to breast, lung, and pelvis by five protocols using current dose reduction methods for routine chest CT and pulmonary CT angiography. MATERIALS AND METHODS: We measured the radiation dose to an anthropomorphic phantom using 64-MDCT with metal oxide semiconductor field effect transistor (MOSFET) detectors in the breast (skin and parenchyma), the lungs, and the pelvis (upper and lower). We compared the following five protocols: protocol 1, 120 kVp, automatic dose modulation, 120-320 mA; protocol 2, 120 kVp, automatic dose modulation, 60-200 mA; protocol 3, 100 kVp and fixed dose of 200 mA; protocol 4, 120 kVp, automatic dose modulation, 200-394 mA; and protocol 5, 80 kVp and fixed dose of 120 mA. Organ doses in milligrays and as a percentage of the volume CT dose index (CTDI(vol)) were compared using the analysis of variance for repeated measurements. RESULTS: Protocol 1 delivered the highest breast dose (mean ± SD, 15.8 ± 1.8 mGy; 110.5% of CTDI(vol)). A decrease in breast radiation of more than 50% was achieved with protocol 3 (4.8 ± 1.8 mGy; 91.7% of CTDI(vol)) compared with protocol 4 (13.1 ± 5.5 mGy; 87.0% of CTDI(vol)) (p = 0.003). The lung received the highest organ dose regardless of the protocol (protocol 4: 21.5 ± 1.7 mGy; 142.5% of CTDI(vol)). Pelvic radiation was low regardless of protocol and did not exceed 0.2 mGy (up to 3.7% of CTDI(vol); p = 0.118-0.999). CONCLUSION: The results of this anthropomorphic phantom study showed substantial and significant variation in radiation doses to the breast and lungs depending on the scanning protocol used with the potential for over threefold dose reduction. SN - 1546-3141 UR - https://www.unboundmedicine.com/medline/citation/21940581/Female_breast_lung_and_pelvic_organ_radiation_from_dose_reduced_64_MDCT_thoracic_examination_protocols:_a_phantom_study_ L2 - http://www.ajronline.org/doi/full/10.2214/AJR.10.6401 DB - PRIME DP - Unbound Medicine ER -