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Brain atrophy caused by vitamin B12-deficient anemia in an infant.
J Pediatr Hematol Oncol. 2011 Oct; 33(7):556-8.JP

Abstract

Vitamin B12 deficiency in infants often presents with nonspecific hematological, gastrointestinal, and neurological manifestations. It is usually caused by inadequate intake, abnormal absorption, or congenital disorders of vitamin B12 metabolism, including transport disorders. We describe a vitamin B12-deficient infant with severe anemia who was breastfed. His mother had undiagnosed vitamin B12 deficiency having undergone total gastrectomy 18 years earlier. The infant developed normally after taking vitamin B12. It is important to suspect vitamin B12 deficiency in mothers who have undergone gastrectomy. Early diagnosis and treatment of vitamin B12 deficiency in infants is important and will help improve long-term prognosis.

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Authors+Show Affiliations

Kamei M
Department of Pediatrics and Neonatology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan. mkamei@med.nagoya-cu.ac.jp
Ito Y
No affiliation info available
Ando N
No affiliation info available
Awaya T
No affiliation info available
Yamada T
No affiliation info available
Nakagawa M
No affiliation info available
Yamaguchi A
No affiliation info available
Ohuchi M
No affiliation info available
Yazaki M
No affiliation info available
Togari H
No affiliation info available

MeSH

Anemia, MegaloblasticAtrophyBrainHumansInfantMaleTreatment OutcomeVitamin B 12Vitamin B 12 Deficiency

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21941150

Citation

Kamei, Michi, et al. "Brain Atrophy Caused By Vitamin B12-deficient Anemia in an Infant." Journal of Pediatric Hematology/oncology, vol. 33, no. 7, 2011, pp. 556-8.
Kamei M, Ito Y, Ando N, et al. Brain atrophy caused by vitamin B12-deficient anemia in an infant. J Pediatr Hematol Oncol. 2011;33(7):556-8.
Kamei, M., Ito, Y., Ando, N., Awaya, T., Yamada, T., Nakagawa, M., Yamaguchi, A., Ohuchi, M., Yazaki, M., & Togari, H. (2011). Brain atrophy caused by vitamin B12-deficient anemia in an infant. Journal of Pediatric Hematology/oncology, 33(7), 556-8. https://doi.org/10.1097/MPH.0b013e31821e5290
Kamei M, et al. Brain Atrophy Caused By Vitamin B12-deficient Anemia in an Infant. J Pediatr Hematol Oncol. 2011;33(7):556-8. PubMed PMID: 21941150.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Brain atrophy caused by vitamin B12-deficient anemia in an infant. AU - Kamei,Michi, AU - Ito,Yasuhiko, AU - Ando,Naoki, AU - Awaya,Tomonari, AU - Yamada,Takaharu, AU - Nakagawa,Motoo, AU - Yamaguchi,Atsuko, AU - Ohuchi,Masanobu, AU - Yazaki,Makoto, AU - Togari,Hajime, PY - 2011/9/24/entrez PY - 2011/9/24/pubmed PY - 2012/2/2/medline SP - 556 EP - 8 JF - Journal of pediatric hematology/oncology JO - J Pediatr Hematol Oncol VL - 33 IS - 7 N2 - Vitamin B12 deficiency in infants often presents with nonspecific hematological, gastrointestinal, and neurological manifestations. It is usually caused by inadequate intake, abnormal absorption, or congenital disorders of vitamin B12 metabolism, including transport disorders. We describe a vitamin B12-deficient infant with severe anemia who was breastfed. His mother had undiagnosed vitamin B12 deficiency having undergone total gastrectomy 18 years earlier. The infant developed normally after taking vitamin B12. It is important to suspect vitamin B12 deficiency in mothers who have undergone gastrectomy. Early diagnosis and treatment of vitamin B12 deficiency in infants is important and will help improve long-term prognosis. SN - 1536-3678 UR - https://www.unboundmedicine.com/medline/citation/21941150/Brain_atrophy_caused_by_vitamin_B12_deficient_anemia_in_an_infant_ L2 - https://doi.org/10.1097/MPH.0b013e31821e5290 DB - PRIME DP - Unbound Medicine ER -