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Cytotoxicity and mechanical behavior of chitin-bentonite clay based polyurethane bio-nanocomposites.
Int J Biol Macromol. 2011 Dec 01; 49(5):1131-6.IJ

Abstract

Chitin based polyurethane bio-nanocomposites (PUBNC) were prepared using chitin, Delite HPS bentonite nanoclay enriched in montmorillonite (MMT), 4,4'-diphenylmethane diisocyanate (MDI) and polycaprolactone polyol CAPA 231 (3000 g/mol(-1)). The prepolymers having different concentration of Delite HPS bentonite nanoclay were extended with 2 moles of chitin. The structures of the resulted polymers were determined by FT-IR technique. The effect of nanoclay contents on mechanical properties and in vitro biocompatibility was investigated. The mechanical properties of the synthesized materials were improved with increase in the Delite HPS bentonite nanoclay contents. Optimum mechanical properties were obtained from the PU bio-nanocomposite samples having 4% Delite HPS bentonite nanoclay. The results revealed that the final PU bio-nanocomposite having 2% Delite HPS bentonite nanoclay contents is ideal contenders for surgical threads with on going investigations into their in vitro biocompatibility, non-toxicity, and mechanical properties.

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Authors+Show Affiliations

Zia KM
Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.
Zuber M
No affiliation info available
Barikani M
No affiliation info available
Hussain R
No affiliation info available
Jamil T
No affiliation info available
Anjum S
No affiliation info available

MeSH

AnimalsBentoniteBiocompatible MaterialsBiotechnologyCell LineCell SurvivalChitinElastomersFibroblastsIsocyanatesMiceMicroscopyNanocompositesPolyestersPolyurethanesSpectroscopy, Fourier Transform InfraredSurface Properties

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21945787

Citation

Zia, Khalid Mahmood, et al. "Cytotoxicity and Mechanical Behavior of Chitin-bentonite Clay Based Polyurethane Bio-nanocomposites." International Journal of Biological Macromolecules, vol. 49, no. 5, 2011, pp. 1131-6.
Zia KM, Zuber M, Barikani M, et al. Cytotoxicity and mechanical behavior of chitin-bentonite clay based polyurethane bio-nanocomposites. Int J Biol Macromol. 2011;49(5):1131-6.
Zia, K. M., Zuber, M., Barikani, M., Hussain, R., Jamil, T., & Anjum, S. (2011). Cytotoxicity and mechanical behavior of chitin-bentonite clay based polyurethane bio-nanocomposites. International Journal of Biological Macromolecules, 49(5), 1131-6. https://doi.org/10.1016/j.ijbiomac.2011.09.010
Zia KM, et al. Cytotoxicity and Mechanical Behavior of Chitin-bentonite Clay Based Polyurethane Bio-nanocomposites. Int J Biol Macromol. 2011 Dec 1;49(5):1131-6. PubMed PMID: 21945787.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cytotoxicity and mechanical behavior of chitin-bentonite clay based polyurethane bio-nanocomposites. AU - Zia,Khalid Mahmood, AU - Zuber,Mohammad, AU - Barikani,Mehdi, AU - Hussain,Rizwan, AU - Jamil,Tahir, AU - Anjum,Sohail, Y1 - 2011/09/16/ PY - 2011/08/09/received PY - 2011/09/05/revised PY - 2011/09/11/accepted PY - 2011/9/28/entrez PY - 2011/9/29/pubmed PY - 2012/2/11/medline SP - 1131 EP - 6 JF - International journal of biological macromolecules JO - Int J Biol Macromol VL - 49 IS - 5 N2 - Chitin based polyurethane bio-nanocomposites (PUBNC) were prepared using chitin, Delite HPS bentonite nanoclay enriched in montmorillonite (MMT), 4,4'-diphenylmethane diisocyanate (MDI) and polycaprolactone polyol CAPA 231 (3000 g/mol(-1)). The prepolymers having different concentration of Delite HPS bentonite nanoclay were extended with 2 moles of chitin. The structures of the resulted polymers were determined by FT-IR technique. The effect of nanoclay contents on mechanical properties and in vitro biocompatibility was investigated. The mechanical properties of the synthesized materials were improved with increase in the Delite HPS bentonite nanoclay contents. Optimum mechanical properties were obtained from the PU bio-nanocomposite samples having 4% Delite HPS bentonite nanoclay. The results revealed that the final PU bio-nanocomposite having 2% Delite HPS bentonite nanoclay contents is ideal contenders for surgical threads with on going investigations into their in vitro biocompatibility, non-toxicity, and mechanical properties. SN - 1879-0003 UR - https://www.unboundmedicine.com/medline/citation/21945787/Cytotoxicity_and_mechanical_behavior_of_chitin_bentonite_clay_based_polyurethane_bio_nanocomposites_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0141-8130(11)00358-8 DB - PRIME DP - Unbound Medicine ER -