Tags

Type your tag names separated by a space and hit enter

A longitudinal three-center study of craniofacial morphology at 6 and 12 years of age in patients with complete bilateral cleft lip and palate.
Clin Oral Investig. 2012 Aug; 16(4):1313-24.CO

Abstract

In this longitudinal study, the craniofacial morphology and evaluated soft tissue profile changes, at 6 and 12 years of age in patients with complete bilateral cleft lip and palate (CBCLP) were compared. Lateral cephalograms from 148 patients with CBCLP, treated consecutively at three European cleft centers, Gothenburg (n (A) = 37), Nijmegen (n (B) = 26), and Oslo (n (C) = 85), were evaluated. Eighteen hard tissue and ten soft tissue landmarks were digitized. Paired t test, Pearson's correlation coefficients, and multiple regression models were applied for statistical analysis. ANOVA and Tukey-B, as a post hoc test, were used to evaluate the increments and compare centers. Hard and soft tissue data were superimposed using the generalized Procrustes analysis. For Nijmegen, the increments of the variables SNA, ANB, SN-NL, SN-ML, NL-ML, Snss, and Snpg were significantly different than the two other centers (p = 0.041 to <0.001). SNPg increments were significantly different between Nijmegen and Oslo (p = 0.002). The three cleft centers followed different treatment protocols, but the main differences in craniofacial morphology until 12 years of age were the growth pattern and the maxillary and upper incisor variables. Follow-up of these patients until facial growth has ceased, which may elucidate components for improving treatment outcome.

Authors+Show Affiliations

Department of Orthodontics and Craniofacial Biology, Cleft Palate Craniofacial Unit, Radboud University Nijmegen Medical Centre, 309 Dentistry, PO Box 9101, 6500 HB Nijmegen, The Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study

Language

eng

PubMed ID

21947868

Citation

Bartzela, Theodosia, et al. "A Longitudinal Three-center Study of Craniofacial Morphology at 6 and 12 Years of Age in Patients With Complete Bilateral Cleft Lip and Palate." Clinical Oral Investigations, vol. 16, no. 4, 2012, pp. 1313-24.
Bartzela T, Katsaros C, Rønning E, et al. A longitudinal three-center study of craniofacial morphology at 6 and 12 years of age in patients with complete bilateral cleft lip and palate. Clin Oral Investig. 2012;16(4):1313-24.
Bartzela, T., Katsaros, C., Rønning, E., Rizell, S., Semb, G., Bronkhorst, E., Halazonetis, D., & Kuijpers-Jagtman, A. M. (2012). A longitudinal three-center study of craniofacial morphology at 6 and 12 years of age in patients with complete bilateral cleft lip and palate. Clinical Oral Investigations, 16(4), 1313-24. https://doi.org/10.1007/s00784-011-0615-y
Bartzela T, et al. A Longitudinal Three-center Study of Craniofacial Morphology at 6 and 12 Years of Age in Patients With Complete Bilateral Cleft Lip and Palate. Clin Oral Investig. 2012;16(4):1313-24. PubMed PMID: 21947868.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A longitudinal three-center study of craniofacial morphology at 6 and 12 years of age in patients with complete bilateral cleft lip and palate. AU - Bartzela,Theodosia, AU - Katsaros,Christos, AU - Rønning,Elisabeth, AU - Rizell,Sara, AU - Semb,Gunvor, AU - Bronkhorst,Ewald, AU - Halazonetis,Demetrios, AU - Kuijpers-Jagtman,Anne Marie, Y1 - 2011/09/24/ PY - 2011/01/09/received PY - 2011/09/07/accepted PY - 2011/9/28/entrez PY - 2011/9/29/pubmed PY - 2013/2/14/medline SP - 1313 EP - 24 JF - Clinical oral investigations JO - Clin Oral Investig VL - 16 IS - 4 N2 - In this longitudinal study, the craniofacial morphology and evaluated soft tissue profile changes, at 6 and 12 years of age in patients with complete bilateral cleft lip and palate (CBCLP) were compared. Lateral cephalograms from 148 patients with CBCLP, treated consecutively at three European cleft centers, Gothenburg (n (A) = 37), Nijmegen (n (B) = 26), and Oslo (n (C) = 85), were evaluated. Eighteen hard tissue and ten soft tissue landmarks were digitized. Paired t test, Pearson's correlation coefficients, and multiple regression models were applied for statistical analysis. ANOVA and Tukey-B, as a post hoc test, were used to evaluate the increments and compare centers. Hard and soft tissue data were superimposed using the generalized Procrustes analysis. For Nijmegen, the increments of the variables SNA, ANB, SN-NL, SN-ML, NL-ML, Snss, and Snpg were significantly different than the two other centers (p = 0.041 to <0.001). SNPg increments were significantly different between Nijmegen and Oslo (p = 0.002). The three cleft centers followed different treatment protocols, but the main differences in craniofacial morphology until 12 years of age were the growth pattern and the maxillary and upper incisor variables. Follow-up of these patients until facial growth has ceased, which may elucidate components for improving treatment outcome. SN - 1436-3771 UR - https://www.unboundmedicine.com/medline/citation/21947868/A_longitudinal_three_center_study_of_craniofacial_morphology_at_6_and_12_years_of_age_in_patients_with_complete_bilateral_cleft_lip_and_palate_ L2 - https://dx.doi.org/10.1007/s00784-011-0615-y DB - PRIME DP - Unbound Medicine ER -