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[Treatment of Plasmodium falciparum malaria in Africa (except cerebral malaria)].
Med Trop (Mars). 1990 Jan-Mar; 50(1):103-8.MT

Abstract

Chloroquine is currently the drug of choice for treatment of acute attacks of Plasmodium falciparum malaria in chloroquine-sensitive areas. In areas of low level resistance, this drug may still be used (25 mg/kg of body weight in three days) in semi-immune patients. In case of failure, or in areas of high level resistance, quinine (25 mg/kg/day for 3 to 5 days) or, in spite of increasing resistance, Fansidar should be prescribed. Mefloquine, Fansimef and Halofantrine ought to be strictly prescribed to delay occurrence of resistance. Severe attacks require quinine by continuous intravenous infusion. Spleen enlargement does not usually require specific treatment unless poor tolerance is observed. Blood transfusions present a considerable risk of HIV transmission. Appropriate malaria treatment may avoid blood transfusions thus preventing HIV dissemination in Africa.

Authors+Show Affiliations

Institut de Médecine et d'Epidémiologie africaines, Hôpital Bichat, Paris, France.No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

2195275

Citation

Charmot, G, and J P. Coulaud. "[Treatment of Plasmodium Falciparum Malaria in Africa (except Cerebral Malaria)]." Medecine Tropicale : Revue Du Corps De Sante Colonial, vol. 50, no. 1, 1990, pp. 103-8.
Charmot G, Coulaud JP. [Treatment of Plasmodium falciparum malaria in Africa (except cerebral malaria)]. Med Trop (Mars). 1990;50(1):103-8.
Charmot, G., & Coulaud, J. P. (1990). [Treatment of Plasmodium falciparum malaria in Africa (except cerebral malaria)]. Medecine Tropicale : Revue Du Corps De Sante Colonial, 50(1), 103-8.
Charmot G, Coulaud JP. [Treatment of Plasmodium Falciparum Malaria in Africa (except Cerebral Malaria)]. Med Trop (Mars). 1990 Jan-Mar;50(1):103-8. PubMed PMID: 2195275.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Treatment of Plasmodium falciparum malaria in Africa (except cerebral malaria)]. AU - Charmot,G, AU - Coulaud,J P, PY - 1990/1/1/pubmed PY - 1990/1/1/medline PY - 1990/1/1/entrez SP - 103 EP - 8 JF - Medecine tropicale : revue du Corps de sante colonial JO - Med Trop (Mars) VL - 50 IS - 1 N2 - Chloroquine is currently the drug of choice for treatment of acute attacks of Plasmodium falciparum malaria in chloroquine-sensitive areas. In areas of low level resistance, this drug may still be used (25 mg/kg of body weight in three days) in semi-immune patients. In case of failure, or in areas of high level resistance, quinine (25 mg/kg/day for 3 to 5 days) or, in spite of increasing resistance, Fansidar should be prescribed. Mefloquine, Fansimef and Halofantrine ought to be strictly prescribed to delay occurrence of resistance. Severe attacks require quinine by continuous intravenous infusion. Spleen enlargement does not usually require specific treatment unless poor tolerance is observed. Blood transfusions present a considerable risk of HIV transmission. Appropriate malaria treatment may avoid blood transfusions thus preventing HIV dissemination in Africa. SN - 0025-682X UR - https://www.unboundmedicine.com/medline/citation/2195275/[Treatment_of_Plasmodium_falciparum_malaria_in_Africa__except_cerebral_malaria_]_ L2 - https://www.diseaseinfosearch.org/result/4415 DB - PRIME DP - Unbound Medicine ER -