Palladium catalyzed stereoselective C-glycosylation of glycals with enol triflates.Org Lett. 2011 Oct 21; 13(20):5648-51.OL
An efficient palladium catalyzed C-glycosylation of glycals with enol triflates has been established. The coupling reactions took place on the anomeric carbon, and the coupling products gave exclusively α isomers. The flexibility of the reaction was exemplified by the broad spectra of substrate scope, constituted of glycals protected with good leaving groups as well as an assortment of enol triflates.