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N-Prolinylanthranilamide pseudopeptides as bifunctional organocatalysts for asymmetric aldol reactions.
Org Lett. 2011 Oct 21; 13(20):5548-51.OL

Abstract

Proline anthranilamide-based pseudopeptides were shown to be effective organocatalysts for enantioselective direct aldol reactions of a selection of aldehydes with various ketones with excellent yield, enantioselectivity up to 99% and anti to syn diastereoselectivity up to 25:1.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Pearson AJ
Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA. ajp4@cwru.edu
Panda S
No affiliation info available

MeSH

AldehydesCatalysisCombinatorial Chemistry TechniquesKetonesMolecular StructurePeptidesProlineStereoisomerismortho-Aminobenzoates

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21958056

Citation

Pearson, Anthony J., and Santanu Panda. "N-Prolinylanthranilamide Pseudopeptides as Bifunctional Organocatalysts for Asymmetric Aldol Reactions." Organic Letters, vol. 13, no. 20, 2011, pp. 5548-51.
Pearson AJ, Panda S. N-Prolinylanthranilamide pseudopeptides as bifunctional organocatalysts for asymmetric aldol reactions. Org Lett. 2011;13(20):5548-51.
Pearson, A. J., & Panda, S. (2011). N-Prolinylanthranilamide pseudopeptides as bifunctional organocatalysts for asymmetric aldol reactions. Organic Letters, 13(20), 5548-51. https://doi.org/10.1021/ol202284n
Pearson AJ, Panda S. N-Prolinylanthranilamide Pseudopeptides as Bifunctional Organocatalysts for Asymmetric Aldol Reactions. Org Lett. 2011 Oct 21;13(20):5548-51. PubMed PMID: 21958056.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - N-Prolinylanthranilamide pseudopeptides as bifunctional organocatalysts for asymmetric aldol reactions. AU - Pearson,Anthony J, AU - Panda,Santanu, Y1 - 2011/09/29/ PY - 2011/10/1/entrez PY - 2011/10/1/pubmed PY - 2011/12/22/medline SP - 5548 EP - 51 JF - Organic letters JO - Org Lett VL - 13 IS - 20 N2 - Proline anthranilamide-based pseudopeptides were shown to be effective organocatalysts for enantioselective direct aldol reactions of a selection of aldehydes with various ketones with excellent yield, enantioselectivity up to 99% and anti to syn diastereoselectivity up to 25:1. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/21958056/N_Prolinylanthranilamide_pseudopeptides_as_bifunctional_organocatalysts_for_asymmetric_aldol_reactions_ L2 - https://doi.org/10.1021/ol202284n DB - PRIME DP - Unbound Medicine ER -