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[The role of a parathyroid hormone analogue in the pathogenesis of malignant hypercalcemia].
Pathol Biol (Paris). 1990 Jun; 38(6):656-64.PB

Abstract

Patients with malignant hypercalcemia can display not only an increase in bone resorption, but also changes in the renal tubular reabsorption of calcium and phosphate similar to those found in primary hyperparathyroidism. A protein of tumoral origin likely responsible for this syndrome has been described. Even if produced by another gene than parathyroid hormone, it shares a homology in the aminoterminus and seems to exert a similar spectrum of action. Besides its role in malignant hypercalcemia, this analogue may be involved in physiological regulatory processes.

Authors+Show Affiliations

Rizzoli R
Département de Médecine, Hôpital Cantonal Universitaire, Genève, Suisse.
Buchs B
No affiliation info available
Pizurki L
No affiliation info available
Caverzasio J
No affiliation info available
Sappino AP
No affiliation info available
Vadas L
No affiliation info available
Arlot M
No affiliation info available
Bonjour JP
No affiliation info available

MeSH

HumansHypercalcemiaHyperparathyroidismNeoplasmsParathyroid HormoneParathyroid Hormone-Related ProteinProteins

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

2197594

Citation

Rizzoli, R, et al. "[The Role of a Parathyroid Hormone Analogue in the Pathogenesis of Malignant Hypercalcemia]." Pathologie-biologie, vol. 38, no. 6, 1990, pp. 656-64.
Rizzoli R, Buchs B, Pizurki L, et al. [The role of a parathyroid hormone analogue in the pathogenesis of malignant hypercalcemia]. Pathol Biol (Paris). 1990;38(6):656-64.
Rizzoli, R., Buchs, B., Pizurki, L., Caverzasio, J., Sappino, A. P., Vadas, L., Arlot, M., & Bonjour, J. P. (1990). [The role of a parathyroid hormone analogue in the pathogenesis of malignant hypercalcemia]. Pathologie-biologie, 38(6), 656-64.
Rizzoli R, et al. [The Role of a Parathyroid Hormone Analogue in the Pathogenesis of Malignant Hypercalcemia]. Pathol Biol (Paris). 1990;38(6):656-64. PubMed PMID: 2197594.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The role of a parathyroid hormone analogue in the pathogenesis of malignant hypercalcemia]. AU - Rizzoli,R, AU - Buchs,B, AU - Pizurki,L, AU - Caverzasio,J, AU - Sappino,A P, AU - Vadas,L, AU - Arlot,M, AU - Bonjour,J P, PY - 1990/6/1/pubmed PY - 1990/6/1/medline PY - 1990/6/1/entrez SP - 656 EP - 64 JF - Pathologie-biologie JO - Pathol Biol (Paris) VL - 38 IS - 6 N2 - Patients with malignant hypercalcemia can display not only an increase in bone resorption, but also changes in the renal tubular reabsorption of calcium and phosphate similar to those found in primary hyperparathyroidism. A protein of tumoral origin likely responsible for this syndrome has been described. Even if produced by another gene than parathyroid hormone, it shares a homology in the aminoterminus and seems to exert a similar spectrum of action. Besides its role in malignant hypercalcemia, this analogue may be involved in physiological regulatory processes. SN - 0369-8114 UR - https://www.unboundmedicine.com/medline/citation/2197594/[The_role_of_a_parathyroid_hormone_analogue_in_the_pathogenesis_of_malignant_hypercalcemia]_ DB - PRIME DP - Unbound Medicine ER -