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Severe community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae in a 6-year-old boy.
Hong Kong Med J. 2011 Oct; 17(5):407-9.HK

Abstract

Mycoplasma pneumoniae is the commonest agent causing atypical pneumonia in children. Macrolides have long been used in the treatment of community-acquired pneumonia not responsive to beta-lactams alone. In this report, we describe the first locally acquired paediatric patient with severe community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae, possessing an A-to-G transition at position 2063 of the 23s rRNA gene. In addition, we have detected two more strains of macrolide-resistant Mycoplasma pneumoniae out of a total of 10 cases with chest infection that were confirmed by polymerase chain reaction. Therefore macrolide-resistant Mycoplasma pneumoniae accounted for 33% (3 out of 10 patients) of the polymerase chain reaction-confirmed cases.

Authors+Show Affiliations

Department of Clinical Pathology, Tuen Mun Hospital, Tuen Mun, Hong Kong. h9910303@yahoo.com.hkNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21979480

Citation

Lung, David C., et al. "Severe Community-acquired Pneumonia Caused By Macrolide-resistant Mycoplasma Pneumoniae in a 6-year-old Boy." Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi, vol. 17, no. 5, 2011, pp. 407-9.
Lung DC, Chan YH, Kwong L, et al. Severe community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae in a 6-year-old boy. Hong Kong Med J. 2011;17(5):407-9.
Lung, D. C., Chan, Y. H., Kwong, L., & Que, T. L. (2011). Severe community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae in a 6-year-old boy. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi, 17(5), 407-9.
Lung DC, et al. Severe Community-acquired Pneumonia Caused By Macrolide-resistant Mycoplasma Pneumoniae in a 6-year-old Boy. Hong Kong Med J. 2011;17(5):407-9. PubMed PMID: 21979480.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Severe community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae in a 6-year-old boy. AU - Lung,David C, AU - Chan,Y H, AU - Kwong,L, AU - Que,T L, PY - 2011/10/8/entrez PY - 2011/10/8/pubmed PY - 2012/2/23/medline SP - 407 EP - 9 JF - Hong Kong medical journal = Xianggang yi xue za zhi JO - Hong Kong Med J VL - 17 IS - 5 N2 - Mycoplasma pneumoniae is the commonest agent causing atypical pneumonia in children. Macrolides have long been used in the treatment of community-acquired pneumonia not responsive to beta-lactams alone. In this report, we describe the first locally acquired paediatric patient with severe community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae, possessing an A-to-G transition at position 2063 of the 23s rRNA gene. In addition, we have detected two more strains of macrolide-resistant Mycoplasma pneumoniae out of a total of 10 cases with chest infection that were confirmed by polymerase chain reaction. Therefore macrolide-resistant Mycoplasma pneumoniae accounted for 33% (3 out of 10 patients) of the polymerase chain reaction-confirmed cases. SN - 1024-2708 UR - https://www.unboundmedicine.com/medline/citation/21979480/Severe_community_acquired_pneumonia_caused_by_macrolide_resistant_Mycoplasma_pneumoniae_in_a_6_year_old_boy_ DB - PRIME DP - Unbound Medicine ER -