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Twenty-year stroke mortality and prediction in twelve cohorts of the Seven Countries Study.
Int J Epidemiol. 1990 Jun; 19(2):309-15.IJ

Abstract

Twelve cohorts of men aged 40-59 for a total of 8287 individuals in six countries (Finland, the Netherlands, Italy, Yugoslavia, Greece and Japan) were examined in the late 1950s or early 1960s for the measurement of some risk factors and then followed up for mortality and causes of death through 20 years. Large differences in 20-year death rates from stroke were recorded among cohorts, with the highest levels in the pool of the Yugoslavia (67 per 1000) and Japanese cohorts (62 per 1000) and the lowest in the Dutch cohort (22 per 1000). The simple linear correlation (among cohorts) of stroke mortality on mean levels at entry of some factors showed inverse significant coefficients for systolic (-0.63) diastolic (-0.51) and mean blood pressure (-0.72), and for serum cholesterol (-0.72), whereas no significant coefficients were found for mean body mass index, mean cigarette consumption and mean physical activity. The Cox model solved for six national pools of cohorts showed that only age and mean blood pressure carry significant positive coefficients, whereas all the other available factors (cigarette consumption, serum cholesterol, body mass index, physical activity) did not approach significant levels except the negative coefficients of smoking habits in Greece.

Authors+Show Affiliations

Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanita, Rome, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study

Language

eng

PubMed ID

2198235

Citation

Menotti, A, et al. "Twenty-year Stroke Mortality and Prediction in Twelve Cohorts of the Seven Countries Study." International Journal of Epidemiology, vol. 19, no. 2, 1990, pp. 309-15.
Menotti A, Keys A, Blackburn H, et al. Twenty-year stroke mortality and prediction in twelve cohorts of the Seven Countries Study. Int J Epidemiol. 1990;19(2):309-15.
Menotti, A., Keys, A., Blackburn, H., Aravanis, C., Dontas, A., Fidanza, F., Giampaoli, S., Karvonen, M., Kromhout, D., & Nedeljkovic, S. (1990). Twenty-year stroke mortality and prediction in twelve cohorts of the Seven Countries Study. International Journal of Epidemiology, 19(2), 309-15.
Menotti A, et al. Twenty-year Stroke Mortality and Prediction in Twelve Cohorts of the Seven Countries Study. Int J Epidemiol. 1990;19(2):309-15. PubMed PMID: 2198235.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Twenty-year stroke mortality and prediction in twelve cohorts of the Seven Countries Study. A1 - Menotti,A, AU - Keys,A, AU - Blackburn,H, AU - Aravanis,C, AU - Dontas,A, AU - Fidanza,F, AU - Giampaoli,S, AU - Karvonen,M, AU - Kromhout,D, AU - Nedeljkovic,S, PY - 1990/6/1/pubmed PY - 1990/6/1/medline PY - 1990/6/1/entrez KW - Age Factors KW - Asia KW - Behavior KW - Biology KW - Causes Of Death KW - Cohort Analysis KW - Comparative Studies KW - Demographic Factors KW - Developed Countries KW - Differential Mortality KW - Eastern Asia KW - Europe KW - Finland KW - Follow-up Studies KW - Greece KW - Italy KW - Japan KW - Mediterranean Countries KW - Mortality KW - Netherlands KW - Northern Europe KW - Population KW - Population Characteristics KW - Population Dynamics KW - Research Methodology KW - Risk Factors KW - Scandinavia KW - Smoking KW - Southern Europe KW - Studies KW - Western Europe KW - Yugoslavia SP - 309 EP - 15 JF - International journal of epidemiology JO - Int J Epidemiol VL - 19 IS - 2 N2 - Twelve cohorts of men aged 40-59 for a total of 8287 individuals in six countries (Finland, the Netherlands, Italy, Yugoslavia, Greece and Japan) were examined in the late 1950s or early 1960s for the measurement of some risk factors and then followed up for mortality and causes of death through 20 years. Large differences in 20-year death rates from stroke were recorded among cohorts, with the highest levels in the pool of the Yugoslavia (67 per 1000) and Japanese cohorts (62 per 1000) and the lowest in the Dutch cohort (22 per 1000). The simple linear correlation (among cohorts) of stroke mortality on mean levels at entry of some factors showed inverse significant coefficients for systolic (-0.63) diastolic (-0.51) and mean blood pressure (-0.72), and for serum cholesterol (-0.72), whereas no significant coefficients were found for mean body mass index, mean cigarette consumption and mean physical activity. The Cox model solved for six national pools of cohorts showed that only age and mean blood pressure carry significant positive coefficients, whereas all the other available factors (cigarette consumption, serum cholesterol, body mass index, physical activity) did not approach significant levels except the negative coefficients of smoking habits in Greece. SN - 0300-5771 UR - https://www.unboundmedicine.com/medline/citation/2198235/Twenty_year_stroke_mortality_and_prediction_in_twelve_cohorts_of_the_Seven_Countries_Study_ L2 - https://academic.oup.com/ije/article-lookup/doi/10.1093/ije/19.2.309 DB - PRIME DP - Unbound Medicine ER -