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[Thromboxane and prostacyclin in endotoxin-induced lung injury].
Zhonghua Jie He He Hu Xi Za Zhi 1990; 13(1):15-7, 61ZJ

Abstract

Hypotension, respiratory failure and ARDS-like pulmonary morphological changes were induced by given continuous intravenous infusion of E. coli endotoxin (1-1.5 micrograms.kg/h) in goats. During endotoxin infusion, plasma TXB2 level rose markedly with peak at 0.5 h and then lowered, while 6-keto-PGF1 alpha elevated progressively with its highest level before death, and correlated with blood pressure and survival times negatively. So we suggested that prostacyclin may be one of the factors responsible for hypotension and death in late period of endotoxin induced shock and lung injury.

Authors+Show Affiliations

304th Hospital of PLA, Beijing.

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

2199081

Citation

Hu, S. "[Thromboxane and Prostacyclin in Endotoxin-induced Lung Injury]." Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases, vol. 13, no. 1, 1990, pp. 15-7, 61.
Hu S. [Thromboxane and prostacyclin in endotoxin-induced lung injury]. Zhonghua Jie He He Hu Xi Za Zhi. 1990;13(1):15-7, 61.
Hu, S. (1990). [Thromboxane and prostacyclin in endotoxin-induced lung injury]. Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases, 13(1), pp. 15-7, 61.
Hu S. [Thromboxane and Prostacyclin in Endotoxin-induced Lung Injury]. Zhonghua Jie He He Hu Xi Za Zhi. 1990;13(1):15-7, 61. PubMed PMID: 2199081.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Thromboxane and prostacyclin in endotoxin-induced lung injury]. A1 - Hu,S, PY - 1990/2/1/pubmed PY - 1990/2/1/medline PY - 1990/2/1/entrez SP - 15-7, 61 JF - Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases JO - Zhonghua Jie He He Hu Xi Za Zhi VL - 13 IS - 1 N2 - Hypotension, respiratory failure and ARDS-like pulmonary morphological changes were induced by given continuous intravenous infusion of E. coli endotoxin (1-1.5 micrograms.kg/h) in goats. During endotoxin infusion, plasma TXB2 level rose markedly with peak at 0.5 h and then lowered, while 6-keto-PGF1 alpha elevated progressively with its highest level before death, and correlated with blood pressure and survival times negatively. So we suggested that prostacyclin may be one of the factors responsible for hypotension and death in late period of endotoxin induced shock and lung injury. SN - 1001-0939 UR - https://www.unboundmedicine.com/medline/citation/2199081/[Thromboxane_and_prostacyclin_in_endotoxin_induced_lung_injury]_ DB - PRIME DP - Unbound Medicine ER -