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Plasma cell balanitis presenting in a patient with a history of syphilis.
Am J Clin Dermatol. 2012 Apr 01; 13(2):129-33.AJ

Abstract

Plasma cell balanitis (PCB), also knows as Zoon balanitis, is a benign asymptomatic but chronic and erosive inflammatory condition of the glans penis and prepuce that generally affects uncircumcised men in later years. Clinical presentation involves a single, shiny, well defined reddish patch. We describe the first case of PCB ever reported in a patient with a previous history of syphilis, and include a review of the current literature. A 57-year-old Hispanic man with a remote history of syphilis presented with a 6-month nonhealing, granulating ulcer of the foreskin and glans penis that had been repeatedly mistaken for syphilis and treated unsuccessfully with circumcision 3 weeks previously. Biopsy of the glans penis demonstrated sections with denuded chronic granulation tissue showing a fibrotic stroma with numerous blood vessels and a mixed inflammatory infiltrate including scattered plasma cells. It is important to differentiate PCB from a syphilitic chancre in a patient presenting with a nonhealing penile lesion. This case report demonstrates that these entities may be seen in the same patient at different times.

Authors+Show Affiliations

Division of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA 90405, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21992223

Citation

Ezra, Navid, et al. "Plasma Cell Balanitis Presenting in a Patient With a History of Syphilis." American Journal of Clinical Dermatology, vol. 13, no. 2, 2012, pp. 129-33.
Ezra N, Binder SW, Behroozan D. Plasma cell balanitis presenting in a patient with a history of syphilis. Am J Clin Dermatol. 2012;13(2):129-33.
Ezra, N., Binder, S. W., & Behroozan, D. (2012). Plasma cell balanitis presenting in a patient with a history of syphilis. American Journal of Clinical Dermatology, 13(2), 129-33. https://doi.org/10.2165/11593260-000000000-00000
Ezra N, Binder SW, Behroozan D. Plasma Cell Balanitis Presenting in a Patient With a History of Syphilis. Am J Clin Dermatol. 2012 Apr 1;13(2):129-33. PubMed PMID: 21992223.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plasma cell balanitis presenting in a patient with a history of syphilis. AU - Ezra,Navid, AU - Binder,Scott W, AU - Behroozan,Daniel, PY - 2011/10/14/entrez PY - 2011/10/14/pubmed PY - 2012/5/23/medline SP - 129 EP - 33 JF - American journal of clinical dermatology JO - Am J Clin Dermatol VL - 13 IS - 2 N2 - Plasma cell balanitis (PCB), also knows as Zoon balanitis, is a benign asymptomatic but chronic and erosive inflammatory condition of the glans penis and prepuce that generally affects uncircumcised men in later years. Clinical presentation involves a single, shiny, well defined reddish patch. We describe the first case of PCB ever reported in a patient with a previous history of syphilis, and include a review of the current literature. A 57-year-old Hispanic man with a remote history of syphilis presented with a 6-month nonhealing, granulating ulcer of the foreskin and glans penis that had been repeatedly mistaken for syphilis and treated unsuccessfully with circumcision 3 weeks previously. Biopsy of the glans penis demonstrated sections with denuded chronic granulation tissue showing a fibrotic stroma with numerous blood vessels and a mixed inflammatory infiltrate including scattered plasma cells. It is important to differentiate PCB from a syphilitic chancre in a patient presenting with a nonhealing penile lesion. This case report demonstrates that these entities may be seen in the same patient at different times. SN - 1179-1888 UR - https://www.unboundmedicine.com/medline/citation/21992223/Plasma_cell_balanitis_presenting_in_a_patient_with_a_history_of_syphilis_ L2 - https://dx.doi.org/10.2165/11593260-000000000-00000 DB - PRIME DP - Unbound Medicine ER -