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Localised prostate cancer - current treatment options.
Aust Fam Physician 2011; 40(10):768-71AF

Abstract

BACKGROUND

A number of options are available to treat localised prostate cancer, with different side effect profiles, effect on quality of life and social costs.

OBJECTIVE

This article outlines the grading and staging of localised prostate cancer and explores the role of each of the treatment options currently available.

DISCUSSION

Treatment selection in localised prostate cancer depends on life expectancy and comorbidities, risk adapted assessment and patient preference. Risk assessment depends on the grade, stage and prostate specific antigen. Options for treatment of localised prostate cancer include active surveillance, radical prostatectomy, curative external beam radiation therapy and brachytherapy. Androgen deprivation therapy in combination with radiation therapy has been shown to increase survival in men with high and high/intermediate risk of occult metastases. Survival rates are essentially equivalent for each modality and are over 90% at 10 years and over 75% at 15 years.

Authors+Show Affiliations

Peter MacCallum Cancer Centre, University of Melbourne and Monash University, Melbourne, Victoria. gillian.duchesne@petermac.org

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22003477

Citation

Duchesne, Gillian. "Localised Prostate Cancer - Current Treatment Options." Australian Family Physician, vol. 40, no. 10, 2011, pp. 768-71.
Duchesne G. Localised prostate cancer - current treatment options. Aust Fam Physician. 2011;40(10):768-71.
Duchesne, G. (2011). Localised prostate cancer - current treatment options. Australian Family Physician, 40(10), pp. 768-71.
Duchesne G. Localised Prostate Cancer - Current Treatment Options. Aust Fam Physician. 2011;40(10):768-71. PubMed PMID: 22003477.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Localised prostate cancer - current treatment options. A1 - Duchesne,Gillian, PY - 2011/10/18/entrez PY - 2011/10/18/pubmed PY - 2012/3/2/medline SP - 768 EP - 71 JF - Australian family physician JO - Aust Fam Physician VL - 40 IS - 10 N2 - BACKGROUND: A number of options are available to treat localised prostate cancer, with different side effect profiles, effect on quality of life and social costs. OBJECTIVE: This article outlines the grading and staging of localised prostate cancer and explores the role of each of the treatment options currently available. DISCUSSION: Treatment selection in localised prostate cancer depends on life expectancy and comorbidities, risk adapted assessment and patient preference. Risk assessment depends on the grade, stage and prostate specific antigen. Options for treatment of localised prostate cancer include active surveillance, radical prostatectomy, curative external beam radiation therapy and brachytherapy. Androgen deprivation therapy in combination with radiation therapy has been shown to increase survival in men with high and high/intermediate risk of occult metastases. Survival rates are essentially equivalent for each modality and are over 90% at 10 years and over 75% at 15 years. SN - 0300-8495 UR - https://www.unboundmedicine.com/medline/citation/22003477/Localised_prostate_cancer___current_treatment_options_ L2 - http://www.racgp.org.au/afp/201110/44355 DB - PRIME DP - Unbound Medicine ER -