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3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online.
Toxicol Lett. 2012 Jan 05; 208(1):12-5.TL

Abstract

The illicit marketplace of substances of abuse continually offers for sale legal alternatives to controlled drugs to a large public. In recent years, a new group of designer drugs, the synthetic cathinones, has emerged as a new trend, particularly among young people. The 3,4-methylenedioxypyrovalerone (MDPV), one of this synthetic compounds, caused an international alert for its cardiovascular and neurological toxicity. This substance, sold as bath salts, has caused many serious intoxications and some deaths in several countries. The aim of this paper is summarise the clinical, pharmacological and toxicological information about this new designer drug.

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Authors+Show Affiliations

Coppola M
Department of Addiction, ASL CN2, Viale Coppino 46, 12051, Alba (CN), Italy. coppolamail@alice.it
Mondola R
No affiliation info available

MeSH

AlkaloidsBenzodioxolesDesigner DrugsDrug and Narcotic ControlGlobal HealthHumansIllicit DrugsInternetMarketingPsychotropic DrugsPyrrolidines

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22008731

Citation

Coppola, M, and R Mondola. "3,4-methylenedioxypyrovalerone (MDPV): Chemistry, Pharmacology and Toxicology of a New Designer Drug of Abuse Marketed Online." Toxicology Letters, vol. 208, no. 1, 2012, pp. 12-5.
Coppola M, Mondola R. 3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online. Toxicol Lett. 2012;208(1):12-5.
Coppola, M., & Mondola, R. (2012). 3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online. Toxicology Letters, 208(1), 12-5. https://doi.org/10.1016/j.toxlet.2011.10.002
Coppola M, Mondola R. 3,4-methylenedioxypyrovalerone (MDPV): Chemistry, Pharmacology and Toxicology of a New Designer Drug of Abuse Marketed Online. Toxicol Lett. 2012 Jan 5;208(1):12-5. PubMed PMID: 22008731.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online. AU - Coppola,M, AU - Mondola,R, Y1 - 2011/10/08/ PY - 2011/08/19/received PY - 2011/10/02/revised PY - 2011/10/03/accepted PY - 2011/10/20/entrez PY - 2011/10/20/pubmed PY - 2012/1/12/medline SP - 12 EP - 5 JF - Toxicology letters JO - Toxicol Lett VL - 208 IS - 1 N2 - The illicit marketplace of substances of abuse continually offers for sale legal alternatives to controlled drugs to a large public. In recent years, a new group of designer drugs, the synthetic cathinones, has emerged as a new trend, particularly among young people. The 3,4-methylenedioxypyrovalerone (MDPV), one of this synthetic compounds, caused an international alert for its cardiovascular and neurological toxicity. This substance, sold as bath salts, has caused many serious intoxications and some deaths in several countries. The aim of this paper is summarise the clinical, pharmacological and toxicological information about this new designer drug. SN - 1879-3169 UR - https://www.unboundmedicine.com/medline/citation/22008731/34_methylenedioxypyrovalerone__MDPV_:_chemistry_pharmacology_and_toxicology_of_a_new_designer_drug_of_abuse_marketed_online_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378-4274(11)01569-4 DB - PRIME DP - Unbound Medicine ER -