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Periconceptional folic acid supplementation among women attending antenatal clinic in Anhui, China: data from a population-based cohort study.
Midwifery 2012; 28(3):291-7M

Abstract

OBJECTIVES

to examine the rate of periconceptional and optimal folic acid supplementation, and to characterise their patterns and determinants among antenatal women in central China.

DESIGN

data from 4290 women in the Anhui Birth Defects and Child Development Cohort Study recruited between October 2008 and September 2009 were analysed.

SETTING

seven Maternal and Child Health Centres of two cities (Hefei and Maanshan) in Anhui province of central China.

PARTICIPANTS

women initiating prenatal care were included and asked to complete a structured questionnaire regarding folic acid supplementation.

FINDINGS

sixty-eight per cent (2905/4290) of pregnant women reported taking folic acid supplementation periconceptionally (i.e. at some point before or during early pregnancy), and 32.8% (1405/4290) and 65.2% (2797/4290) had taken it before or during early pregnancy, respectively. However, only 16.1% (690/4290) used it optimally (i.e. regularly from four weeks before pregnancy throughout four weeks after pregnancy). Use of periconceptional folic acid was significantly associated with educational level, household income, registered residence, age, gestational age at recruitment, and planning of pregnancy.

CONCLUSION

optimal folic acid supplementation was relatively low.

IMPLICATIONS FOR PRACTICE

further efforts are needed to inform the population and promote the use of folic acid supplementation.

Authors+Show Affiliations

Anhui Provincial Key Laboratory of Population Health and Aristogenics, Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei 230032, China. xiuya_2000@sina.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22015219

Citation

Xing, Xiu-Ya, et al. "Periconceptional Folic Acid Supplementation Among Women Attending Antenatal Clinic in Anhui, China: Data From a Population-based Cohort Study." Midwifery, vol. 28, no. 3, 2012, pp. 291-7.
Xing XY, Tao FB, Hao JH, et al. Periconceptional folic acid supplementation among women attending antenatal clinic in Anhui, China: data from a population-based cohort study. Midwifery. 2012;28(3):291-7.
Xing, X. Y., Tao, F. B., Hao, J. H., Huang, K., Huang, Z. H., Zhu, X. M., ... Sun, Y. (2012). Periconceptional folic acid supplementation among women attending antenatal clinic in Anhui, China: data from a population-based cohort study. Midwifery, 28(3), pp. 291-7. doi:10.1016/j.midw.2011.04.002.
Xing XY, et al. Periconceptional Folic Acid Supplementation Among Women Attending Antenatal Clinic in Anhui, China: Data From a Population-based Cohort Study. Midwifery. 2012;28(3):291-7. PubMed PMID: 22015219.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Periconceptional folic acid supplementation among women attending antenatal clinic in Anhui, China: data from a population-based cohort study. AU - Xing,Xiu-Ya, AU - Tao,Fang-Biao, AU - Hao,Jia-Hu, AU - Huang,Kun, AU - Huang,Zhao-Hui, AU - Zhu,Xiao-Ming, AU - Xiao,Li-Min, AU - Cheng,Dai-Juan, AU - Su,Pu-Yu, AU - Zhu,Peng, AU - Xu,Yuan-Yuan, AU - Sun,Ying, Y1 - 2011/10/19/ PY - 2010/07/16/received PY - 2011/04/08/revised PY - 2011/04/11/accepted PY - 2011/10/22/entrez PY - 2011/10/22/pubmed PY - 2012/10/12/medline SP - 291 EP - 7 JF - Midwifery JO - Midwifery VL - 28 IS - 3 N2 - OBJECTIVES: to examine the rate of periconceptional and optimal folic acid supplementation, and to characterise their patterns and determinants among antenatal women in central China. DESIGN: data from 4290 women in the Anhui Birth Defects and Child Development Cohort Study recruited between October 2008 and September 2009 were analysed. SETTING: seven Maternal and Child Health Centres of two cities (Hefei and Maanshan) in Anhui province of central China. PARTICIPANTS: women initiating prenatal care were included and asked to complete a structured questionnaire regarding folic acid supplementation. FINDINGS: sixty-eight per cent (2905/4290) of pregnant women reported taking folic acid supplementation periconceptionally (i.e. at some point before or during early pregnancy), and 32.8% (1405/4290) and 65.2% (2797/4290) had taken it before or during early pregnancy, respectively. However, only 16.1% (690/4290) used it optimally (i.e. regularly from four weeks before pregnancy throughout four weeks after pregnancy). Use of periconceptional folic acid was significantly associated with educational level, household income, registered residence, age, gestational age at recruitment, and planning of pregnancy. CONCLUSION: optimal folic acid supplementation was relatively low. IMPLICATIONS FOR PRACTICE: further efforts are needed to inform the population and promote the use of folic acid supplementation. SN - 1532-3099 UR - https://www.unboundmedicine.com/medline/citation/22015219/Periconceptional_folic_acid_supplementation_among_women_attending_antenatal_clinic_in_Anhui_China:_data_from_a_population_based_cohort_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0266-6138(11)00045-3 DB - PRIME DP - Unbound Medicine ER -