Tags

Type your tag names separated by a space and hit enter

Host and environmental reservoirs of infection for bovine digital dermatitis treponemes.
Vet Microbiol. 2012 Apr 23; 156(1-2):102-9.VM

Abstract

Bovine digital dermatitis (BDD) is a global infectious disease causing lameness of cattle and is responsible for substantial animal welfare issues and economic losses. The causative agents are considered to be spirochetal bacteria belonging to the genus Treponema, which have consistently been identified in BDD lesions worldwide. One potential means of controlling infection is the disruption of transmission; however, the infection reservoirs and transmission routes of BDD treponemes have yet to be elucidated. To address these issues, we surveyed for evidence of BDD treponeme presence in the dairy farm environment, in bovine tissues and in bovine gastrointestinal (GI) tract contents. A total of 368 samples were tested using PCR assays specific for each of three currently recognised, isolated phylotypes of BDD treponemes. All environmental samples, together with insects and GI tract content samples were negative for BDD treponeme DNA from the three phylotypes. However, we identified BDD treponemes in two non-pedal bovine regions: the oral cavity (14.3% of cattle tested) and the rectum (14.8% of cattle tested). Whilst only single phylotypes were detected in the oral cavity, two of the rectal tissues yielded DNA from more than one phylotype, with one sample yielding all three BDD treponeme phylotypes. Whilst it might be considered that direct skin to skin contact may be a major transmission route of BDD treponemes, further studies are required to characterise and determine the potential contribution of oral and rectal carriage to BDD transmission.

Authors+Show Affiliations

Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, Liverpool L69 7ZJ, UK. evansnj@liverpool.ac.ukNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22019292

Citation

Evans, Nicholas J., et al. "Host and Environmental Reservoirs of Infection for Bovine Digital Dermatitis Treponemes." Veterinary Microbiology, vol. 156, no. 1-2, 2012, pp. 102-9.
Evans NJ, Timofte D, Isherwood DR, et al. Host and environmental reservoirs of infection for bovine digital dermatitis treponemes. Vet Microbiol. 2012;156(1-2):102-9.
Evans, N. J., Timofte, D., Isherwood, D. R., Brown, J. M., Williams, J. M., Sherlock, K., Lehane, M. J., Murray, R. D., Birtles, R. J., Hart, C. A., & Carter, S. D. (2012). Host and environmental reservoirs of infection for bovine digital dermatitis treponemes. Veterinary Microbiology, 156(1-2), 102-9. https://doi.org/10.1016/j.vetmic.2011.09.029
Evans NJ, et al. Host and Environmental Reservoirs of Infection for Bovine Digital Dermatitis Treponemes. Vet Microbiol. 2012 Apr 23;156(1-2):102-9. PubMed PMID: 22019292.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Host and environmental reservoirs of infection for bovine digital dermatitis treponemes. AU - Evans,Nicholas J, AU - Timofte,Dorina, AU - Isherwood,Diana R, AU - Brown,Jennifer M, AU - Williams,Jonathan M, AU - Sherlock,Kenneth, AU - Lehane,Michael J, AU - Murray,Richard D, AU - Birtles,Richard J, AU - Hart,C Anthony, AU - Carter,Stuart D, Y1 - 2011/10/02/ PY - 2011/05/24/received PY - 2011/09/23/revised PY - 2011/09/27/accepted PY - 2011/10/25/entrez PY - 2011/10/25/pubmed PY - 2012/8/3/medline SP - 102 EP - 9 JF - Veterinary microbiology JO - Vet. Microbiol. VL - 156 IS - 1-2 N2 - Bovine digital dermatitis (BDD) is a global infectious disease causing lameness of cattle and is responsible for substantial animal welfare issues and economic losses. The causative agents are considered to be spirochetal bacteria belonging to the genus Treponema, which have consistently been identified in BDD lesions worldwide. One potential means of controlling infection is the disruption of transmission; however, the infection reservoirs and transmission routes of BDD treponemes have yet to be elucidated. To address these issues, we surveyed for evidence of BDD treponeme presence in the dairy farm environment, in bovine tissues and in bovine gastrointestinal (GI) tract contents. A total of 368 samples were tested using PCR assays specific for each of three currently recognised, isolated phylotypes of BDD treponemes. All environmental samples, together with insects and GI tract content samples were negative for BDD treponeme DNA from the three phylotypes. However, we identified BDD treponemes in two non-pedal bovine regions: the oral cavity (14.3% of cattle tested) and the rectum (14.8% of cattle tested). Whilst only single phylotypes were detected in the oral cavity, two of the rectal tissues yielded DNA from more than one phylotype, with one sample yielding all three BDD treponeme phylotypes. Whilst it might be considered that direct skin to skin contact may be a major transmission route of BDD treponemes, further studies are required to characterise and determine the potential contribution of oral and rectal carriage to BDD transmission. SN - 1873-2542 UR - https://www.unboundmedicine.com/medline/citation/22019292/Host_and_environmental_reservoirs_of_infection_for_bovine_digital_dermatitis_treponemes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378-1135(11)00539-6 DB - PRIME DP - Unbound Medicine ER -