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[Clinical curative effect and factor analysis of depression treated by acupuncture].
Zhongguo Zhen Jiu. 2011 Oct; 31(10):875-8.ZZ

Abstract

OBJECTIVE

To evaluate the curative effect of primary depression treated with the main points of Back-shu points of Five-zang and Geshu (BL 17) according to the differentiation.

METHODS

Sixty cases of primary depression were randomly divided into an acupuncture group (31 cases) and a western medication group (29 cases). In acupuncture group, Back-shu points of Five-zang and Geshu (BL 17) were applied as the main points, Taichong (LR 3) and Sanyinjiao (SP 6) were added for stagnation of liver qi and spleen deficiency; Shenmen (HT 7) and Sanyinjiao (SP 6) were added for deficiency of both heart and spleen according to the differentiation. In western medication group, Fluoxetine Hydrochloride capsule was taken by oral administration for 20 mg, once a day. The treatment lasted for 6 weeks in both groups. After 2, 4, and 6 weeks treatment, the clinical curative effects of both groups were assessed by Hamilton Depression (HAMD) Rating Scale, HAMD Factor Analysis and Asberg Side Effect Scale.

RESULTS

After 6 weeks treatment, the total effective rate was 67.7% (21/31) in acupuncture group and 65.5% (19/29) in western medication group, indicating the close curative effects(P > 0.05). After 2, 4, and 6 weeks treatment, the HAMD score, scores of anxious somatization, sleeping and retardation factors were significantly reduced (all P < 0.01) in two groups, through the comparison at different time points between two groups, scores of anxious somatization, sleeping factors in acupuncture group were superior to those in western medication group (both P < 0.05), but score of retardation factor in western medication group was superior to that in acupuncture group (P < 0.05). The Asberg Side Effect Scale in western medication group arrived at peak at thesecond week, and then reduced slowly; the side effect in acupuncture group was low and steady, and lower than that in western medication group after 6 week treatment (P < 0.05).

CONCLUSION

The curative effect of depression with acupuncture based on differentiation is equal to that of Fluoxetine Hydrochloride capsule with oral administration, while the side effect is milder than that of Fluoxetine Hydrochloride capsule.

Authors+Show Affiliations

Department of Acupuncture and Moxibustion, Beijing TCM Hospital Affiliated to Capital Medical University, Beijing 100010, China.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

22043670

Citation

Ma, Qin, et al. "[Clinical Curative Effect and Factor Analysis of Depression Treated By Acupuncture]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 31, no. 10, 2011, pp. 875-8.
Ma Q, Zhou DA, Wang LP. [Clinical curative effect and factor analysis of depression treated by acupuncture]. Zhongguo Zhen Jiu. 2011;31(10):875-8.
Ma, Q., Zhou, D. A., & Wang, L. P. (2011). [Clinical curative effect and factor analysis of depression treated by acupuncture]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 31(10), 875-8.
Ma Q, Zhou DA, Wang LP. [Clinical Curative Effect and Factor Analysis of Depression Treated By Acupuncture]. Zhongguo Zhen Jiu. 2011;31(10):875-8. PubMed PMID: 22043670.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical curative effect and factor analysis of depression treated by acupuncture]. AU - Ma,Qin, AU - Zhou,De-An, AU - Wang,Lin-Peng, PY - 2011/11/3/entrez PY - 2011/11/3/pubmed PY - 2011/12/21/medline SP - 875 EP - 8 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 31 IS - 10 N2 - OBJECTIVE: To evaluate the curative effect of primary depression treated with the main points of Back-shu points of Five-zang and Geshu (BL 17) according to the differentiation. METHODS: Sixty cases of primary depression were randomly divided into an acupuncture group (31 cases) and a western medication group (29 cases). In acupuncture group, Back-shu points of Five-zang and Geshu (BL 17) were applied as the main points, Taichong (LR 3) and Sanyinjiao (SP 6) were added for stagnation of liver qi and spleen deficiency; Shenmen (HT 7) and Sanyinjiao (SP 6) were added for deficiency of both heart and spleen according to the differentiation. In western medication group, Fluoxetine Hydrochloride capsule was taken by oral administration for 20 mg, once a day. The treatment lasted for 6 weeks in both groups. After 2, 4, and 6 weeks treatment, the clinical curative effects of both groups were assessed by Hamilton Depression (HAMD) Rating Scale, HAMD Factor Analysis and Asberg Side Effect Scale. RESULTS: After 6 weeks treatment, the total effective rate was 67.7% (21/31) in acupuncture group and 65.5% (19/29) in western medication group, indicating the close curative effects(P > 0.05). After 2, 4, and 6 weeks treatment, the HAMD score, scores of anxious somatization, sleeping and retardation factors were significantly reduced (all P < 0.01) in two groups, through the comparison at different time points between two groups, scores of anxious somatization, sleeping factors in acupuncture group were superior to those in western medication group (both P < 0.05), but score of retardation factor in western medication group was superior to that in acupuncture group (P < 0.05). The Asberg Side Effect Scale in western medication group arrived at peak at thesecond week, and then reduced slowly; the side effect in acupuncture group was low and steady, and lower than that in western medication group after 6 week treatment (P < 0.05). CONCLUSION: The curative effect of depression with acupuncture based on differentiation is equal to that of Fluoxetine Hydrochloride capsule with oral administration, while the side effect is milder than that of Fluoxetine Hydrochloride capsule. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/22043670/[Clinical_curative_effect_and_factor_analysis_of_depression_treated_by_acupuncture]_ L2 - http://www.diseaseinfosearch.org/result/2199 DB - PRIME DP - Unbound Medicine ER -