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Synthesis by precipitation polymerization of molecularly imprinted polymer for the selective extraction of diclofenac from water samples.
J Hazard Mater. 2011 Dec 30; 198:175-81.JH

Abstract

A molecularly imprinted polymer (MIP) was synthesized by precipitation polymerization using diclofenac (DFC) as a template, 2-vinylpyridine (2-VP) as functional monomer, ethylene glycol dimethacrylate (EGDMA) as cross-linker, and toluene as porogen. The MIP showed outstanding affinity toward DFC in aqueous solution with a binding site capacity (Q(max)) of 324.8 mg/g (1.09 mmol/g) and was used as solid-phase extraction (SPE) material for the quantitative enrichment of DFC in environmental water samples and off-line coupled to a reversed-phase HPLC/DAD. Various parameters including washing solvent, elution solvent and breakthrough volume affecting the extraction efficiency of the polymers have been evaluated to achieve the selective preconcentration of DFC from water samples and to reduce non-specific interactions. Recoveries of DFC extracted from tap water, river water and wastewater samples were higher than 95%, and no significant DFC recovery difference was obtained among the different water matrix. The stability of MIP was tested by consecutive percolation of water sample, and it was shown that the performance of the MIP did not vary even after 30 adsorption and desorption cycles. Furthermore, the MISPE was used for the analysis of DFC in river water and wastewater samples and revealed DFC concentrations of 0.69±0.002 μg/L (n=3) and 0.31±0.004μg/L (n=3), respectively. The results were in good agreement with corresponding LC-MS/MS data.

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Authors+Show Affiliations

Dai CM
College of Civil Engineering, Tongji University, Shanghai, China.
Zhou XF
No affiliation info available
Zhang YL
No affiliation info available
Liu SG
No affiliation info available
Zhang J
No affiliation info available

MeSH

Anti-Inflammatory Agents, Non-SteroidalChromatography, High Pressure LiquidDiclofenacMicroscopy, Electron, ScanningPolymersWater Pollutants, Chemical

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22050930

Citation

Dai, Chao-meng, et al. "Synthesis By Precipitation Polymerization of Molecularly Imprinted Polymer for the Selective Extraction of Diclofenac From Water Samples." Journal of Hazardous Materials, vol. 198, 2011, pp. 175-81.
Dai CM, Zhou XF, Zhang YL, et al. Synthesis by precipitation polymerization of molecularly imprinted polymer for the selective extraction of diclofenac from water samples. J Hazard Mater. 2011;198:175-81.
Dai, C. M., Zhou, X. F., Zhang, Y. L., Liu, S. G., & Zhang, J. (2011). Synthesis by precipitation polymerization of molecularly imprinted polymer for the selective extraction of diclofenac from water samples. Journal of Hazardous Materials, 198, 175-81. https://doi.org/10.1016/j.jhazmat.2011.10.027
Dai CM, et al. Synthesis By Precipitation Polymerization of Molecularly Imprinted Polymer for the Selective Extraction of Diclofenac From Water Samples. J Hazard Mater. 2011 Dec 30;198:175-81. PubMed PMID: 22050930.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis by precipitation polymerization of molecularly imprinted polymer for the selective extraction of diclofenac from water samples. AU - Dai,Chao-meng, AU - Zhou,Xue-fei, AU - Zhang,Ya-lei, AU - Liu,Shu-guang, AU - Zhang,Juan, Y1 - 2011/10/15/ PY - 2011/07/11/received PY - 2011/08/30/revised PY - 2011/10/06/accepted PY - 2011/11/5/entrez PY - 2011/11/5/pubmed PY - 2012/4/3/medline SP - 175 EP - 81 JF - Journal of hazardous materials JO - J Hazard Mater VL - 198 N2 - A molecularly imprinted polymer (MIP) was synthesized by precipitation polymerization using diclofenac (DFC) as a template, 2-vinylpyridine (2-VP) as functional monomer, ethylene glycol dimethacrylate (EGDMA) as cross-linker, and toluene as porogen. The MIP showed outstanding affinity toward DFC in aqueous solution with a binding site capacity (Q(max)) of 324.8 mg/g (1.09 mmol/g) and was used as solid-phase extraction (SPE) material for the quantitative enrichment of DFC in environmental water samples and off-line coupled to a reversed-phase HPLC/DAD. Various parameters including washing solvent, elution solvent and breakthrough volume affecting the extraction efficiency of the polymers have been evaluated to achieve the selective preconcentration of DFC from water samples and to reduce non-specific interactions. Recoveries of DFC extracted from tap water, river water and wastewater samples were higher than 95%, and no significant DFC recovery difference was obtained among the different water matrix. The stability of MIP was tested by consecutive percolation of water sample, and it was shown that the performance of the MIP did not vary even after 30 adsorption and desorption cycles. Furthermore, the MISPE was used for the analysis of DFC in river water and wastewater samples and revealed DFC concentrations of 0.69±0.002 μg/L (n=3) and 0.31±0.004μg/L (n=3), respectively. The results were in good agreement with corresponding LC-MS/MS data. SN - 1873-3336 UR - https://www.unboundmedicine.com/medline/citation/22050930/Synthesis_by_precipitation_polymerization_of_molecularly_imprinted_polymer_for_the_selective_extraction_of_diclofenac_from_water_samples_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0304-3894(11)01267-2 DB - PRIME DP - Unbound Medicine ER -