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Optimal waist circumference cutoff value for defining the metabolic syndrome in postmenopausal Latin American women.
Menopause. 2012 Apr; 19(4):433-7.M

Abstract

OBJECTIVE

The aim of this study was to determine an optimal waist circumference (WC) cutoff value for defining the metabolic syndrome (METS) in postmenopausal Latin American women.

METHODS

A total of 3,965 postmenopausal women (age, 45-64 y), with self-reported good health, attending routine consultation at 12 gynecological centers in major Latin American cities were included in this cross-sectional study. Modified guidelines of the US National Cholesterol Education Program, Adult Treatment Panel III were used to assess METS risk factors. Receiver operator characteristic curve analysis was used to obtain an optimal WC cutoff value best predicting at least two other METS components. Optimal cutoff values were calculated by plotting the true-positive rate (sensitivity) against the false-positive rate (1 - specificity). In addition, total accuracy, distance to receiver operator characteristic curve, and the Youden Index were calculated.

RESULTS

Of the participants, 51.6% (n = 2,047) were identified as having two or more nonadipose METS risk components (excluding a positive WC component). These women were older, had more years since menopause onset, used hormone therapy less frequently, and had higher body mass indices than women with fewer metabolic risk factors. The optimal WC cutoff value best predicting at least two other METS components was determined to be 88 cm, equal to that defined by the Adult Treatment Panel III.

CONCLUSIONS

A WC cutoff value of 88 cm is optimal for defining METS in this postmenopausal Latin American series.

Authors+Show Affiliations

Instituto de Biomedicina, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22067278

Citation

Blümel, Juan E., et al. "Optimal Waist Circumference Cutoff Value for Defining the Metabolic Syndrome in Postmenopausal Latin American Women." Menopause (New York, N.Y.), vol. 19, no. 4, 2012, pp. 433-7.
Blümel JE, Legorreta D, Chedraui P, et al. Optimal waist circumference cutoff value for defining the metabolic syndrome in postmenopausal Latin American women. Menopause. 2012;19(4):433-7.
Blümel, J. E., Legorreta, D., Chedraui, P., Ayala, F., Bencosme, A., Danckers, L., Lange, D., Espinoza, M. T., Gomez, G., Grandia, E., Izaguirre, H., Manriquez, V., Martino, M., Navarro, D., Ojeda, E., Onatra, W., Pozzo, E., Prada, M., Royer, M., ... Zuñiga, C. (2012). Optimal waist circumference cutoff value for defining the metabolic syndrome in postmenopausal Latin American women. Menopause (New York, N.Y.), 19(4), 433-7. https://doi.org/10.1097/gme.0b013e318231fc79
Blümel JE, et al. Optimal Waist Circumference Cutoff Value for Defining the Metabolic Syndrome in Postmenopausal Latin American Women. Menopause. 2012;19(4):433-7. PubMed PMID: 22067278.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Optimal waist circumference cutoff value for defining the metabolic syndrome in postmenopausal Latin American women. AU - Blümel,Juan E, AU - Legorreta,Deborah, AU - Chedraui,Peter, AU - Ayala,Felix, AU - Bencosme,Ascanio, AU - Danckers,Luis, AU - Lange,Diego, AU - Espinoza,Maria T, AU - Gomez,Gustavo, AU - Grandia,Elena, AU - Izaguirre,Humberto, AU - Manriquez,Valentin, AU - Martino,Mabel, AU - Navarro,Daysi, AU - Ojeda,Eliana, AU - Onatra,William, AU - Pozzo,Estela, AU - Prada,Mariela, AU - Royer,Monique, AU - Saavedra,Javier M, AU - Sayegh,Fabiana, AU - Tserotas,Konstantinos, AU - Vallejo,Maria S, AU - Zuñiga,Cristina, AU - ,, PY - 2011/11/10/entrez PY - 2011/11/10/pubmed PY - 2012/8/2/medline SP - 433 EP - 7 JF - Menopause (New York, N.Y.) JO - Menopause VL - 19 IS - 4 N2 - OBJECTIVE: The aim of this study was to determine an optimal waist circumference (WC) cutoff value for defining the metabolic syndrome (METS) in postmenopausal Latin American women. METHODS: A total of 3,965 postmenopausal women (age, 45-64 y), with self-reported good health, attending routine consultation at 12 gynecological centers in major Latin American cities were included in this cross-sectional study. Modified guidelines of the US National Cholesterol Education Program, Adult Treatment Panel III were used to assess METS risk factors. Receiver operator characteristic curve analysis was used to obtain an optimal WC cutoff value best predicting at least two other METS components. Optimal cutoff values were calculated by plotting the true-positive rate (sensitivity) against the false-positive rate (1 - specificity). In addition, total accuracy, distance to receiver operator characteristic curve, and the Youden Index were calculated. RESULTS: Of the participants, 51.6% (n = 2,047) were identified as having two or more nonadipose METS risk components (excluding a positive WC component). These women were older, had more years since menopause onset, used hormone therapy less frequently, and had higher body mass indices than women with fewer metabolic risk factors. The optimal WC cutoff value best predicting at least two other METS components was determined to be 88 cm, equal to that defined by the Adult Treatment Panel III. CONCLUSIONS: A WC cutoff value of 88 cm is optimal for defining METS in this postmenopausal Latin American series. SN - 1530-0374 UR - https://www.unboundmedicine.com/medline/citation/22067278/Optimal_waist_circumference_cutoff_value_for_defining_the_metabolic_syndrome_in_postmenopausal_Latin_American_women_ L2 - https://doi.org/10.1097/gme.0b013e318231fc79 DB - PRIME DP - Unbound Medicine ER -