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Asp Viper (Vipera aspis) envenomation: experience of the Marseille Poison Centre from 1996 to 2008.
Toxins (Basel). 2009 12; 1(2):100-12.T

Abstract

A retrospective case review study of viper envenomations collected by the Marseille's Poison Centre between 1996 and 2008 was performed.

RESULTS

174 cases were studied (52 grade 1 = G1, 90 G2 and 32 G3). G1 patients received symptomatic treatments (average hospital stay 0.96 day). One hundred and six (106) of the G2/G3 patients were treated with the antivenom Viperfav* (2.1+/-0.9 days in hospital), while 15 of them received symptomatic treatments only (plus one immediate death) (8.1+/-4 days in hospital, 2 of them died). The hospital stay was significantly reduced in the antivenom treated group (p < 0.001), and none of the 106 antivenom treated patients had immediate (anaphylaxis) or delayed (serum sickness) allergic reactions.

CONCLUSION

Viperfav* antivenom was safe and effective for treating asp viper venom-induced toxicity.

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Authors+Show Affiliations

de Haro L
Centre Antipoison, hôpital Salvator, 249 boulevard Sainte Marguerite, 13009 Marseille, France. luc.deharo@ap-hm.fr
Glaizal M
No affiliation info available
Tichadou L
No affiliation info available
Blanc-Brisset I
No affiliation info available
Hayek-Lanthois M
No affiliation info available

MeSH

AnimalsAntiveninsHumansPoisonsRetrospective StudiesSnake BitesViper VenomsViperidae

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22069534

Citation

de Haro, Luc, et al. "Asp Viper (Vipera Aspis) Envenomation: Experience of the Marseille Poison Centre From 1996 to 2008." Toxins, vol. 1, no. 2, 2009, pp. 100-12.
de Haro L, Glaizal M, Tichadou L, et al. Asp Viper (Vipera aspis) envenomation: experience of the Marseille Poison Centre from 1996 to 2008. Toxins (Basel). 2009;1(2):100-12.
de Haro, L., Glaizal, M., Tichadou, L., Blanc-Brisset, I., & Hayek-Lanthois, M. (2009). Asp Viper (Vipera aspis) envenomation: experience of the Marseille Poison Centre from 1996 to 2008. Toxins, 1(2), 100-12. https://doi.org/10.3390/toxins1020100
de Haro L, et al. Asp Viper (Vipera Aspis) Envenomation: Experience of the Marseille Poison Centre From 1996 to 2008. Toxins (Basel). 2009;1(2):100-12. PubMed PMID: 22069534.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Asp Viper (Vipera aspis) envenomation: experience of the Marseille Poison Centre from 1996 to 2008. AU - de Haro,Luc, AU - Glaizal,Mathieu, AU - Tichadou,Lucia, AU - Blanc-Brisset,Ingrid, AU - Hayek-Lanthois,Maryvonne, Y1 - 2009/11/24/ PY - 2009/10/09/received PY - 2009/11/18/revised PY - 2009/11/23/accepted PY - 2011/11/10/entrez PY - 2009/12/1/pubmed PY - 2009/12/1/medline KW - asp viper KW - Vipera genus KW - antivenom KW - neurotoxins KW - snake envenomation SP - 100 EP - 12 JF - Toxins JO - Toxins (Basel) VL - 1 IS - 2 N2 - UNLABELLED: A retrospective case review study of viper envenomations collected by the Marseille's Poison Centre between 1996 and 2008 was performed. RESULTS: 174 cases were studied (52 grade 1 = G1, 90 G2 and 32 G3). G1 patients received symptomatic treatments (average hospital stay 0.96 day). One hundred and six (106) of the G2/G3 patients were treated with the antivenom Viperfav* (2.1+/-0.9 days in hospital), while 15 of them received symptomatic treatments only (plus one immediate death) (8.1+/-4 days in hospital, 2 of them died). The hospital stay was significantly reduced in the antivenom treated group (p < 0.001), and none of the 106 antivenom treated patients had immediate (anaphylaxis) or delayed (serum sickness) allergic reactions. CONCLUSION: Viperfav* antivenom was safe and effective for treating asp viper venom-induced toxicity. SN - 2072-6651 UR - https://www.unboundmedicine.com/medline/citation/22069534/Asp_Viper__Vipera_aspis__envenomation:_experience_of_the_Marseille_Poison_Centre_from_1996_to_2008_ L2 - https://www.mdpi.com/resolver?pii=toxins1020100 DB - PRIME DP - Unbound Medicine ER -