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Ruthenium-catalyzed C-H/N-O bond functionalization: green isoquinolone syntheses in water.
Org Lett. 2011 Dec 16; 13(24):6548-51.OL

Abstract

Ruthenium-catalyzed isoquinolone syntheses with ample scope were accomplished through carboxylate assistance in environmentally benign water as a reaction medium. The high chemoselectivity of the ruthenium(II) carboxylate complex also set the stage for the direct use of free hydroxamic acids for annulations of alkynes.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Ackermann L
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität, Tammannstrasse 2, 37077 Göttingen, Germany. Lutz.Ackermann@chemie.uni-goettingen.de
Fenner S
No affiliation info available

MeSH

AlkynesBenzamidesCarboxylic AcidsCatalysisColorimetryIsoquinolinesMolecular StructureRutheniumWater

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22077379

Citation

Ackermann, Lutz, and Sabine Fenner. "Ruthenium-catalyzed C-H/N-O Bond Functionalization: Green Isoquinolone Syntheses in Water." Organic Letters, vol. 13, no. 24, 2011, pp. 6548-51.
Ackermann L, Fenner S. Ruthenium-catalyzed C-H/N-O bond functionalization: green isoquinolone syntheses in water. Org Lett. 2011;13(24):6548-51.
Ackermann, L., & Fenner, S. (2011). Ruthenium-catalyzed C-H/N-O bond functionalization: green isoquinolone syntheses in water. Organic Letters, 13(24), 6548-51. https://doi.org/10.1021/ol202861k
Ackermann L, Fenner S. Ruthenium-catalyzed C-H/N-O Bond Functionalization: Green Isoquinolone Syntheses in Water. Org Lett. 2011 Dec 16;13(24):6548-51. PubMed PMID: 22077379.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ruthenium-catalyzed C-H/N-O bond functionalization: green isoquinolone syntheses in water. AU - Ackermann,Lutz, AU - Fenner,Sabine, Y1 - 2011/11/11/ PY - 2011/11/15/entrez PY - 2011/11/15/pubmed PY - 2012/2/22/medline SP - 6548 EP - 51 JF - Organic letters JO - Org Lett VL - 13 IS - 24 N2 - Ruthenium-catalyzed isoquinolone syntheses with ample scope were accomplished through carboxylate assistance in environmentally benign water as a reaction medium. The high chemoselectivity of the ruthenium(II) carboxylate complex also set the stage for the direct use of free hydroxamic acids for annulations of alkynes. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/22077379/Ruthenium_catalyzed_C_H/N_O_bond_functionalization:_green_isoquinolone_syntheses_in_water_ L2 - https://doi.org/10.1021/ol202861k DB - PRIME DP - Unbound Medicine ER -