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Interaction of silver nanoparticles with biological surfaces of Caenorhabditis elegans.
Ecotoxicol Environ Saf. 2012 Mar; 77:64-70.EE

Abstract

Silver nanoparticles (AgNPs) are being used in an increasing number of industrial and commercial applications; this has resulted in an increased release of AgNPs into the environment. Understanding the interaction of AgNPs with biological surfaces is important, as such understanding will facilitate predictions of the further effects of nanoparticles on biological systems. This study highlights the interaction of citrate-coated silver nanoparticles (cAgNPs) with the biological surfaces of the nematode C. elegans. General toxicity, as proxied by factors such as mortality and reproduction, was evaluated in nematode growth medium (NGM), which provides a more homogeneous distribution of cAgNPs than in K-medium. The survival and reproduction of C. elegans evidenced a clear reduction in up to 100 mg/L and 10 mg/L of cAgNPs, respectively. We also noted significant interactions of cAgNPs with the biological surfaces of C. elegans. Severe epidemic edema and burst were detected in the exposure group, which may be associated with secondary infections in soil ecosystems. We observed no evidence of cAgNPs intake by C. elegans. This is, to the best of our knowledge, the first report to investigate the nanotoxicity of cAgNPs as related to biological surfaces of C. elegans; further research is needed to study the fate of cAgNPs inside of C. elegans.

Authors+Show Affiliations

Department of Environmental Science, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 143-701, Korea.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22078113

Citation

Kim, Shin Woong, et al. "Interaction of Silver Nanoparticles With Biological Surfaces of Caenorhabditis Elegans." Ecotoxicology and Environmental Safety, vol. 77, 2012, pp. 64-70.
Kim SW, Nam SH, An YJ. Interaction of silver nanoparticles with biological surfaces of Caenorhabditis elegans. Ecotoxicol Environ Saf. 2012;77:64-70.
Kim, S. W., Nam, S. H., & An, Y. J. (2012). Interaction of silver nanoparticles with biological surfaces of Caenorhabditis elegans. Ecotoxicology and Environmental Safety, 77, 64-70. https://doi.org/10.1016/j.ecoenv.2011.10.023
Kim SW, Nam SH, An YJ. Interaction of Silver Nanoparticles With Biological Surfaces of Caenorhabditis Elegans. Ecotoxicol Environ Saf. 2012;77:64-70. PubMed PMID: 22078113.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Interaction of silver nanoparticles with biological surfaces of Caenorhabditis elegans. AU - Kim,Shin Woong, AU - Nam,Sun-Hwa, AU - An,Youn-Joo, Y1 - 2011/11/09/ PY - 2011/06/30/received PY - 2011/10/18/revised PY - 2011/10/25/accepted PY - 2011/11/15/entrez PY - 2011/11/15/pubmed PY - 2012/3/9/medline SP - 64 EP - 70 JF - Ecotoxicology and environmental safety JO - Ecotoxicol Environ Saf VL - 77 N2 - Silver nanoparticles (AgNPs) are being used in an increasing number of industrial and commercial applications; this has resulted in an increased release of AgNPs into the environment. Understanding the interaction of AgNPs with biological surfaces is important, as such understanding will facilitate predictions of the further effects of nanoparticles on biological systems. This study highlights the interaction of citrate-coated silver nanoparticles (cAgNPs) with the biological surfaces of the nematode C. elegans. General toxicity, as proxied by factors such as mortality and reproduction, was evaluated in nematode growth medium (NGM), which provides a more homogeneous distribution of cAgNPs than in K-medium. The survival and reproduction of C. elegans evidenced a clear reduction in up to 100 mg/L and 10 mg/L of cAgNPs, respectively. We also noted significant interactions of cAgNPs with the biological surfaces of C. elegans. Severe epidemic edema and burst were detected in the exposure group, which may be associated with secondary infections in soil ecosystems. We observed no evidence of cAgNPs intake by C. elegans. This is, to the best of our knowledge, the first report to investigate the nanotoxicity of cAgNPs as related to biological surfaces of C. elegans; further research is needed to study the fate of cAgNPs inside of C. elegans. SN - 1090-2414 UR - https://www.unboundmedicine.com/medline/citation/22078113/Interaction_of_silver_nanoparticles_with_biological_surfaces_of_Caenorhabditis_elegans_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0147-6513(11)00365-4 DB - PRIME DP - Unbound Medicine ER -